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Table 3 Post mortem diagnosis in RLN of sheep with experimental BSE in preclinical and clinical status*.

From: Rapid and discriminatory diagnosis of scrapie and BSE in retro-pharyngeal lymph nodes of sheep

sheep nr. m.p.i. at euthanasia IHC WB
2117 6 - 2+
6869 9 + 1+
2114 12 + 2+
3903 13 + 2+
3907 15 + 2+
3905 17 + 2+
2112 19 + 2+
2140 21§ + 2+
2115 21§ + 2+
2138 23§ + 2+
2116 24§ + 2+
  1. * Oral inoculations occurred between 4–6 mo of age. Each animal received 5 g of bovine BSEinfected brain by oral route [27].
  2. Positive in tonsil and RLN.
  3. 1+, weak signal for all three PrPres bands. 2+ PrPres bands clearly visible. Results after concentration obtained with either of the antibodies 9A2 or L42; antibody 12B2 scored negative in all samples.
  4. §Clinical signs.
  5. Weakly positive in tonsil and ileal Peyer's patches.