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Table 4 Groups of piglets with different injections at different time points 1

From: Anti-idiotypic antibodies reduce efficacy of the attenuated vaccine against highly pathogenic PRRSV challenge

Time points2 Groups of piglets received injections1
  1 2 3 4 5 6
0 Mab2-5G2 aAb2s 7H12 normal swine IgG PBS PBS
143 CH-1R CH-1R CH-1R CH-1R PBS PBS
28 CH-1R CH-1R CH-1R CH-1R PBS PBS
424 HP-PRRSV HP-PRRSV HP-PRRSV HP-PRRSV HP-PRRSV PBS
  1. 1The amount of IgG each piglet received was 100 μg/kg of body weight and PBS was 2 mls via intramuscularly (i.m.) injection.
  2. 2The numbers were the days post injection (DPI). 42 DPI was also the 0 days post challenge (DPC).
  3. 3On 14 DPI, the piglets received CH-1R, the attenuated PRRSV vaccine and generated from CH-1a, a North American type strain isolated from China (GenBank no. EU807840) [24] i.m. on the left side of the neck at 2 doses/piglet diluted in 2 ml of PBS.
  4. 4On 42 DPI, the piglets were challenged with HP-PRRSV HuN4 strain at 3 × 105 TCID50/piglet and also considered as 0 days post challenge (DPC).