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Table 3 Neutralizing antibodies detected from sera collected on different DPIs and DPCs

From: Anti-idiotypic antibodies reduce efficacy of the attenuated vaccine against highly pathogenic PRRSV challenge

DPIs/DPCs  Titers of neutralizing antibodies from six groups of piglets1
  1 2 3 4 5 6
DPIs       
0 0 (6) 2 0 (6) 0 (6) 0 (6) 0 (6) 0 (6)
7 0 (6) 0 (6) 0 (6) 0 (6) 0 (6) 0 (6)
14 0 (6) 0 (6) 0 (6) 0 (6) 0 (6) 0 (6)
21 2.3 (6) 2.7 (6) 0 (6) 0 (6) 0 (6) 0 (6)
28 3.3 (6) 3.3 (6) 0(6) 0 (6) 0 (6) 0 (6)
35 3.3 (6) 3.7 (6) 4.7 (6) 5.3 (6) 0 (6) 0 (6)
DPCs       
0 3.7 (6) 3.7 (6) 6 (6) 6.3 (6) 0 (6) 0 (6)
3 2.7 (6) 3.3 (6) 5.3 (6) 5.3 (6) 0 (6) 0 (6)
7 3.3 (6) 3.3 (6) 5.3 (6) 6 (6) 0 (6) 0 (6)
10 3.3 (6) 3.3 (6) 6.7 (6) 8 (6) 0 (6) 0 (6)
14 3.7 (6) 4.7 (6) 8.7 (6) 10.1(6) 5.3 (6) 0 (6)
21 6 (2) 6.7 (3) 10.7 (3) 13.3 (3) 12 (2) 0 (3)
  1. 1Neutralizing antibodies were detected to evaluate the ability of antibodies against Mab2-5G2 and aAb2s to neutralize PRRSV infection of Marc-145 cells. Briefly, a 2-fold diluted serum sample and a titer of 100 TCID50/mL was incubated for 1 h at 37°C and was transferred to a 96-well plate containing a Marc-145 cell monolayer. Neutralizing antibody titers were defined as the mean of reciprocal of the highest dilution of sera that inhibited 50% CPE.
  2. 2Each number represents the mean dilution of neutralizing antibody titers generated from six groups of piglets on different DPIs/DPCs. The numbers in parentheses were the numbers of piglets measured on different DPIs/DPCs.