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Table 3 Percentage of cpAC and normal lung biospecimens with TKR phosphorylation

From: Canine pulmonary adenocarcinoma tyrosine kinase receptor expression and phosphorylation

TKR cpAC n(%) Normal lung n(%)
EGFR 11 (92) 10 (83)
HER2 12 (100) 11 (92)
HER3 12 (100) 12 (100)
FGFR1 10 (83) 9 (75)
FGFR3 10 (83) 10 (83)
FGFR4 10 (83) 9 (75)
InsR 11 (92) 12 (100)
IGF-IR 12 (100) 12 (100)
TrkA/NTRK1 12 (100) 11 (92)
TrkB/NTRK2 12 (100) 11 (92)
Met/HGFR 10 (83) 10 (83)
Ron/MST1R 11 (92) 10 (83)
Ret 10 (83) 12 (100)
ALK 11 (92) 11 (92)
PDGFR 11 (92) 10 (83)
c-KIT/SCFR 6 (50) 11 (92)
FLT3/Flk2 7 (58) 11 (92)
M-CSFR 9 (75) 11 (83)
EphA1 11 (92) 12 (100)
EphA2 11 (92) 11 (92)
EphA3 11 (92) 11 (92)
EphB1 11 (92) 10 (83)
EphB3 12 (100) 10 (83)
EphB4 11 (92) 11 (92)
Tyro-3/Dtk 11 (92) 10 (83)
Axl 7 (58) 12 (100)
Tie/TEK 12 (100) 12 (100)
VEGFR2/KDR 6 (50) 11 (92)
  1. Phosphorylation of biospecimen protein lysate was determined by the presence of fluorescence that was quantified after normalization to the array spotted positive and negative controls for each sample. Each receptor was assayed in duplicates and the mean fluorescence for that receptor was recorded. n, represents the number of positive samples and (%) represents the percentage out of 12 total samples.