Table 4 Molecular scores and interactions of avilamycin (AVI) against Gallus gallus interleukin 1 receptor accessory protein (IL1RAP; AlphaFold ID: A0A1D5P4S3), interleukin 1 receptor type 2 (IL1R2; AlphaFold ID: A0A1L1RVR1), interleukin-1 receptor-associated kinase-like 2 (IRAK2; AlphaFold ID: F1N826), and interleukin-17 receptor D (IL17RD; AlphaFold ID: Q7T2L7)
From: Dietary lysozyme and avilamycin modulate gut health, immunity, and growth rate in broilers
| Â | Docking scores | Molecular interactions |
|---|---|---|
IL1RAP | -9.12 | Hydrogen: HIS382, VAL383, TRP385, GLU387, ARG393, ARG466, LYS499, and ARG534. Charge: LEU545 |
IL1R2 | -7.32 | Hydrogen: LYS75, PRO77, SER78, ASP160, ALA162, and LYS250 Charge: LYS75 Hydrophobic: PHE60, TYR63, and LYS75 |
IRAK2 | -8.27 | Hydrogen: THR242, ARG379, TYR381, and LYS395 Hydrophobic: ARG379, TYR381, MET391, PHE609, and TRP611 |
IL17RD | -9.19 | Hydrogen: GLY43, ARG44, SER47, LYS51, ILE85, and GLU148 Hydrophobic: ARG44, LYS51, TYR88, and LEU99 |