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  1. The objective of the present study was to optimize and validate an automated method to assess the total antioxidant capacity (TAC) in serum of dogs using the cupric reducing antioxidant capacity (CUPRAC) metho...

    Authors: Camila Peres Rubio, Asta Tvarijonaviciute, Silvia Martinez-Subiela, Josefa Hernández-Ruiz and José Joaquin Cerón
    Citation: BMC Veterinary Research 2016 12:137
  2. The release of new DNA-based diagnostic tools has increased tremendously in companion animals. Over 70 different DNA variants are now known for the cat, including DNA variants in disease-associated genes and g...

    Authors: Leslie A. Lyons, Robert A. Grahn, Francesca Genova, Michela Beccaglia, John J. Hopwood and Maria Longeri
    Citation: BMC Veterinary Research 2016 12:136
  3. Platelet-rich plasma (PRP) preparations are a common treatment in equine osteoarthritis (OA). However, there are controversies regarding the ideal concentration of platelets and leukocytes in these biological ...

    Authors: Jorge U. Carmona, Diana L. Ríos, Catalina López, María E. Álvarez, Jorge E. Pérez and Mabel E. Bohórquez
    Citation: BMC Veterinary Research 2016 12:135
  4. Aujeszky’s disease is a viral disease of suids caused by Suid Herpesvirus 1. The disease has worldwide distribution with significant economic impact. In Serbia, there is neither an Aujeszky’s disease eradication ...

    Authors: V. Milicevic, S. Radojicic, M. Valcic, V. Ivovic and V. Radosavljevic
    Citation: BMC Veterinary Research 2016 12:134
  5. Sheeppox (SPP) is one of the priorities, high-impact animal diseases in many developing countries, where live attenuated vaccines are routinely used against sheeppox virus (SPPV). In an event of an SPP outbrea...

    Authors: Zineb Boumart, Samira Daouam, Imane Belkourati, Lamya Rafi, Eeva Tuppurainen, Khalid Omari Tadlaoui and Mehdi El Harrak
    Citation: BMC Veterinary Research 2016 12:133
  6. Interest in porcine epidemic diarrhea has grown since the 2013 outbreak in the United States caused major losses, with mortality rates up to 100 % in suckling piglets. In Mexico, an outbreak of porcine epidemi...

    Authors: María Elena Trujillo-Ortega, Rolando Beltrán-Figueroa, Montserrat Elemi García-Hernández, Mireya Juárez-Ramírez, Alicia Sotomayor-González, Erika N. Hernández-Villegas, José F. Becerra-Hernández and Rosa Elena Sarmiento-Silva
    Citation: BMC Veterinary Research 2016 12:132
  7. Methicillin-resistant Staphylococcus pseudintermedius (MRSP) has emerged globally in companion animals in the last decade. In Europe, the multidrug-resistant sequence type (ST)71 is widespread, but recently other...

    Authors: Peter Damborg, Arshnee Moodley, Bent Aalbæk, Gianpiero Ventrella, Teresa Pires dos Santos and Luca Guardabassi
    Citation: BMC Veterinary Research 2016 12:131
  8. Research in cats has shown that increased fermentation-derived propionic acid and its metabolites can be used as alternative substrates for gluconeogenesis, thus sparing amino acids for other purposes. This am...

    Authors: Wendy Wambacq, Galena Rybachuk, Isabelle Jeusette, Kristel Rochus, Brigitte Wuyts, Veerle Fievez, Patrick Nguyen and Myriam Hesta
    Citation: BMC Veterinary Research 2016 12:130
  9. From the beginning of the 21st century Enterococcus cecorum has emerged as a significant health problem for poultry raised under intensive production systems. To obtain new insights into this bacterial species, w...

    Authors: Beata Dolka, Dorota Chrobak-Chmiel, László Makrai and Piotr Szeleszczuk
    Citation: BMC Veterinary Research 2016 12:129
  10. Long-term high-concentrate diet (HCD) feeding can cause subacute ruminal acidosis in cows and subsequently trigger systemic inflammatory and immune responses. Therefore, we conducted the present study in which...

    Authors: Di Jin, Guangjun Chang, Kai Zhang, Junfei Guo, Tianle Xu and Xiangzhen Shen
    Citation: BMC Veterinary Research 2016 12:128
  11. Common carp (Cyprinus carpio L.), one of the most economically valuable commercial farming fish species in China, is often infected by a variety of viruses. As the first line of defence against microbial pathogen...

    Authors: Yaoyao Zhu, Chenchen Qi, Shijuan Shan, Fumiao Zhang, Hua Li, Liguo An and Guiwen Yang
    Citation: BMC Veterinary Research 2016 12:127
  12. New therapeutic strategies are needed to face the rapid spread of multidrug-resistant staphylococci in veterinary medicine. The objective of this study was to identify synergies between antimicrobial and non-a...

    Authors: Rikke Prejh Brochmann, Alexandra Helmfrid, Bimal Jana, Zofia Magnowska and Luca Guardabassi
    Citation: BMC Veterinary Research 2016 12:126
  13. In Japan, epizootic arboviral infections have severely impacted the livestock industry for a long period. Akabane, Aino, Chuzan, bovine ephemeral fever and Ibaraki viruses have repeatedly caused epizootic abno...

    Authors: Tomoko Kato, Tohru Yanase, Moemi Suzuki, Yoshito Katagiri, Kazufumi Ikemiyagi, Katsunori Takayoshi, Hiroaki Shirafuji, Seiichi Ohashi, Kazuo Yoshida, Makoto Yamakawa and Tomoyuki Tsuda
    Citation: BMC Veterinary Research 2016 12:125
  14. Combined use of angiotensin-converting enzyme inhibitors and nonsteroidal anti-inflammatory drugs may induce acute kidney injury in humans, especially when combined with diuretics. The objective of this invest...

    Authors: Jonathan N. King, Alessandro Panteri, Melanie Graille, Wolfgang Seewald, Gabriele Friton and Cyril Desevaux
    Citation: BMC Veterinary Research 2016 12:124
  15. The objective of this study was to determine the effect of ketoprofen on acute phase protein (APPs) concentrations in goats undergoing castration. A total of 16 clinically healthy, male and 12 months old goats...

    Authors: Umit Karademir, Ibrahim Akin, Hasan Erdogan, Kerem Ural and Gamze Sevri Ekren Asici
    Citation: BMC Veterinary Research 2016 12:123
  16. Congenital stationary night-blindness (CSNB) is a recessive autosomal defect in low-light vision in Appaloosa and other horse breeds. This condition has been mapped by linkage analysis to a gene coding for the...

    Authors: Michelle L. Scott, Emily E. John, Rebecca R. Bellone, John C. H. Ching, Matthew E. Loewen, Lynne S. Sandmeyer, Bruce H. Grahn and George W. Forsyth
    Citation: BMC Veterinary Research 2016 12:121
  17. Electrical potentials generated in the central nervous system in response to brief visual stimuli, flash visual evoked potentials (FVEPs), can be recorded non-invasively over the occipital cortex. FVEPs are us...

    Authors: L. Ström and B. Ekesten
    Citation: BMC Veterinary Research 2016 12:120
  18. Bovine Leukemia Virus (BLV) produces disorders on the immune system in naturally infected animals, which may counteract the development of immunity after vaccination. The aim of this study was to investigate w...

    Authors: Rodrigo Puentes, Laureana De Brun, Agustina Algorta, Valeria Da Silva, Florencia Mansilla, Gustavo Sacco, Silvia Llambí and Alejandra V. Capozzo
    Citation: BMC Veterinary Research 2016 12:119
  19. The temporal sensitivity of the surveillance system (TemSSe) for Bovine Viral Diarrhea (BVD) in Danish dairy herds was evaluated. Currently, the Danish antibody blocking ELISA is used to test quarterly bulk ta...

    Authors: Alessandro Foddai, Anders Stockmarr and Anette Boklund
    Citation: BMC Veterinary Research 2016 12:118
  20. Horses are much predisposed and susceptible to excessive and acute inflammatory responses that cause the recruitment and stimulation of polymorphnuclear granulocytes (PMN) together with peripheral blood mononu...

    Authors: Simon Rütten, Gerald F. Schusser, Getu Abraham and Wieland Schrödl
    Citation: BMC Veterinary Research 2016 12:117
  21. Diarrhea is one of the most common clinical symptoms reported in companion animal clinics. Dog circovirus (DogCV) is a new mammalian circovirus that is considered to be a cause of alimentary syndromes such as ...

    Authors: Han-Siang Hsu, Ting-Han Lin, Hung-Yi Wu, Lee-Shuan Lin, Cheng-Shu Chung, Ming-Tang Chiou and Chao-Nan Lin
    Citation: BMC Veterinary Research 2016 12:116
  22. Disseminated infection and bacteraemia is an underreported and under-researched aspect of Johne’s disease. This is mainly due to the time it takes for Mycobacterium avium subsp. paratuberculosis (MAP) to grow and...

    Authors: Benjamin M. C. Swift, Jonathan N. Huxley, Karren M. Plain, Douglas J. Begg, Kumudika de Silva, Auriol C. Purdie, Richard J. Whittington and Catherine E. D. Rees
    Citation: BMC Veterinary Research 2016 12:115
  23. Inflammatory bowel disease (IBD) refers to a diverse group of chronic gastrointestinal diseases, and gut microbial dysbiosis has been proposed as a modulating factor in its pathogenesis. Several studies have i...

    Authors: Jia Xu, Adronie Verbrugghe, Marta Lourenço, Geert P. J. Janssens, Daisy J. X. Liu, Tom Van de Wiele, Venessa Eeckhaut, Filip Van Immerseel, Isabel Van de Maele, Yufeng Niu, Guido Bosch, Greet Junius, Brigitte Wuyts and Myriam Hesta
    Citation: BMC Veterinary Research 2016 12:114
  24. Newcastle disease (ND) is one of the most contagious and devastating diseases to poultry in the world. The causative agents are virulent strains of Newcastle disease virus (NDV), which belong to the genus Avul...

    Authors: Jie Zhu, Shunlin Hu, Haixu Xu, Jingjing Liu, Zhenzhen Zhao, Xiaoquan Wang and Xiufan Liu
    Citation: BMC Veterinary Research 2016 12:113
  25. Fracture healing in bone gap is one of the major challenges encountered in Orthopedic Surgery. At present, the treatment includes bone graft, employing either internal or external fixation which has a signific...

    Authors: Mohd Rafiq Mohd Ibrahim, Simmrat Singh, Azhar Mahmood Merican, Hanumantha Rao Balaji Raghavendran, Malliga Raman Murali, Sangeetha Vasudevaraj Naveen and Tunku Kamarul
    Citation: BMC Veterinary Research 2016 12:112
  26. Acute Idiopathic Polyradiculoneuritis, an animal model for the axonal form of the Guillain – Barre Syndrome in humans and the acquired myasthenia gravis are different autoimmune disorders affecting the periphe...

    Authors: Gabriela Dumitrita Stanciu and Gheorghe Solcan
    Citation: BMC Veterinary Research 2016 12:111
  27. Feeding alfalfa hay is often recommended for its buffering components, like protein and calcium, to prevent lesions of the gastric mucosa in horses. Until now, there has been no information regarding the influ...

    Authors: Sarah Vondran, Monica Venner and Ingrid Vervuert
    Citation: BMC Veterinary Research 2016 12:110
  28. This paper presents an unusual form of disseminated Mycobacterium tuberculosis infection in a dog. The infection lasted at least one year and its main gross lesions were massive cardiac tuberculomas. To the best ...

    Authors: Olga Szaluś-Jordanow, Ewa Augustynowicz-Kopeć, Michał Czopowicz, Arkadiusz Olkowski, Andrzej Łobaczewski, Magdalena Rzewuska, Rafał Sapierzyński, Elżbieta Wiatr, Magdalena Garncarz and Tadeusz Frymus
    Citation: BMC Veterinary Research 2016 12:109
  29. Based on the prodrug principle, aspirin and eugenol, as starting precursors, were esterified to synthesize aspirin eugenol ester (AEE). The aim of the present study was to evaluate the antithrombotic effect of...

    Authors: Ning Ma, Xi-Wang Liu, Ya-Jun Yang, Dong-Shuai Shen, Xiao-Le Zhao, Isam Mohamed, Xiao-Jun Kong and Jian-Yong Li
    Citation: BMC Veterinary Research 2016 12:108
  30. Lameness represents the third most important health-related cause of economic loss in the dairy industry after fertility and mastitis. Although, dairy Mediterranean Buffaloes (MB) and dairy cows share similar ...

    Authors: Jacopo Guccione, Christian Carcasole, Maher Alsaaod, Luigi D’Andrea, Antonio Di Loria, Angela De Rosa, Paolo Ciaramella and Adrian Steiner
    Citation: BMC Veterinary Research 2016 12:107
  31. In humans, the presence of antiphospholipid antibodies (aPL) is frequently found in immune thrombocytopenia. The present study investigated whether aPL and any aPL subtypes are associated with canine thrombocy...

    Authors: Yu-Chen Chen, Lang-Ming Chi, Kuan-Chih Chow, Shiow-Her Chiou, Yi-Hsin Fan, Shu-Peng Ho, Yu-Chen Hsu, Yu-Chyi Hwang, Meng-Xing Wu, Wei-Ming Lee, Shiun-Long Lin, Chau-Loong Tsang and Frank Chiahung Mao
    Citation: BMC Veterinary Research 2016 12:106
  32. Patent ductus arteriosus (PDA) is one of the most common congenital heart defects in dogs and is considered to be a complex, polygenic threshold trait for which a female sex predisposition has been described. ...

    Authors: Marjolein L. den Toom, Agnes E. Meiling, Rachel E. Thomas, Peter A. J. Leegwater and Henri C. M. Heuven
    Citation: BMC Veterinary Research 2016 12:105
  33. Cardiac troponin-I assays have been validated in horses.’High-sensitivity’ cardiac troponin assays are now the standard in human cardiology. Objective: Appropriately validate the’high-sensitivity’ cardiac Troponi...

    Authors: E. Shields, I. Seiden-Long, S. Massie, S. Passante and R. Leguillette
    Citation: BMC Veterinary Research 2016 12:104
  34. Evaluating beneficial effects of potential protective therapies following cardiac arrest in rodent models could be enhanced by exploring behavior and cognitive functions. The Morris Water Maze is a well-known ...

    Authors: Wolfgang Weihs, Alexandra-M Warenits, Florian Ettl, Ingrid A. M. Magnet, Ursula Teubenbacher, Andreas Hilpold, Andreas Schober, Christoph Testori, Akos Tiboldi, Katharina Tillmann Mag, Michael Holzer, Sandra Hoegler, Andreas Janata and Fritz Sterz
    Citation: BMC Veterinary Research 2016 12:103
  35. Castration is one of the most common procedures performed on beef and dairy cattle. The objective of the study was to determine the efficacy of meloxicam oral suspension in reducing pain and inflammation in ca...

    Authors: M. E. Olson, Brenda Ralston, Les Burwash, Heather Matheson-Bird and Nick D. Allan
    Citation: BMC Veterinary Research 2016 12:102
  36. Bovine necrohemorrhagic enteritis is caused by Clostridium perfringens type A. Due to the rapid progress and fatal outcome of the disease, vaccination would be of high value. In this study, C. perfringens toxins,...

    Authors: Evy Goossens, Stefanie Verherstraeten, Bonnie R. Valgaeren, Bart Pardon, Leen Timbermont, Stijn Schauvliege, Diego Rodrigo-Mocholí, Freddy Haesebrouck, Richard Ducatelle, Piet R. Deprez and Filip Van Immerseel
    Citation: BMC Veterinary Research 2016 12:101
  37. Lethal chondrodysplasia (bulldog syndrome) is a well-known congenital syndrome in cattle and occurs sporadically in many breeds. In 2015, it was noticed that about 12 % of the offspring of the phenotypically n...

    Authors: Jørgen S. Agerholm, Fiona Menzi, Fintan J. McEvoy, Vidhya Jagannathan and Cord Drögemüller
    Citation: BMC Veterinary Research 2016 12:100
  38. Longitudinal samples from two production sites were used to (1) describe the pattern of PEDV shedding (rRT-PCR) in individual rectal swabs, pen fecal samples, and pen oral fluids (OF); (2) describe the kinetic...

    Authors: Jordan Bjustrom-Kraft, Katie Woodard, Luis Giménez-Lirola, Marisa Rotolo, Chong Wang, Yaxuan Sun, Peter Lasley, Jianqiang Zhang, David Baum, Phillip Gauger, Rodger Main and Jeffrey Zimmerman
    Citation: BMC Veterinary Research 2016 12:99
  39. As we reported previously, Getah virus infection occurred in horses at the Miho training center of the Japan Racing Association in 2014. This was the first outbreak after a 31-year absence in Japan. Here, we r...

    Authors: Hiroshi Bannai, Akihiro Ochi, Manabu Nemoto, Koji Tsujimura, Takashi Yamanaka and Takashi Kondo
    Citation: BMC Veterinary Research 2016 12:98
  40. In this study, two traits related with resistance to gastrointestinal nematodes (GIN) were measured in 529 adult sheep: faecal egg count (FEC) and activity of immunoglobulin A in plasma (IgA). In dry years, FE...

    Authors: M. Atlija, J. M. Prada, B. Gutiérrez-Gil, F. A. Rojo-Vázquez, M. J. Stear, J. J. Arranz and M. Martínez-Valladares
    Citation: BMC Veterinary Research 2016 12:97
  41. Immune thrombocytopenia (ITP) in dogs is analogous to that in humans. Romiplostim, a novel thrombopoietin receptor (TPO-R) agonist, is currently used for the treatment of refractory ITP in humans, but not in d...

    Authors: Barbara Kohn, Gürkan Bal, Aleksandra Chirek, Sina Rehbein and Abdulgabar Salama
    Citation: BMC Veterinary Research 2016 12:96

    The Erratum to this article has been published in BMC Veterinary Research 2016 12:290

  42. A novel porcine deltacoronavirus (PDCoV), also known as porcine coronavirus HKU15, was reported in China in 2012 and identified in the U.S. in early 2014. Since then, PDCoV has been identified in a number of U...

    Authors: Faten Okda, Steven Lawson, Xiaodong Liu, Aaron Singrey, Travis Clement, Kyle Hain, Julie Nelson, Jane Christopher-Hennings and Eric A. Nelson
    Citation: BMC Veterinary Research 2016 12:95
  43. Avian infectious bronchitis (IB) is one of the most important viral diseases of poultry, affecting chickens of all ages and causing major economic losses in poultry flocks. Mass vaccination is conducted in Mor...

    Authors: Khadija Khataby, Faouzi Kichou, Chafiqa Loutfi and My Mustapha Ennaji
    Citation: BMC Veterinary Research 2016 12:94
  44. This study assessed the effects of sedation using a combination of fentanyl, midazolam and medetomidine in comparison to ketamine. Rhesus Macaques (Macaca mulatta), (n = 16, 5 males and 3 females randomly allocat...

    Authors: Henri G. M. J. Bertrand, Yvette C. Ellen, Stevie O’Keefe and Paul A. Flecknell
    Citation: BMC Veterinary Research 2016 12:93
  45. Retrievers are dogs particularly bred to retrieve birds or other small game, for the retrieval, the dogs are typically sent to the place where the shot game has fallen or to search the field for the wounded bu...

    Authors: Barbara Bockstahler, Alexander Tichy and Patricia Aigner
    Citation: BMC Veterinary Research 2016 12:92
  46. The slaughter of pregnant cattle and the fate of the foetuses are relatively new subjects in the field of animal welfare. The Scientific Committee on Veterinary Measures relating to Public Health (SCVPH), howe...

    Authors: Patric Maurer, Ernst Lücker and Katharina Riehn
    Citation: BMC Veterinary Research 2016 12:91
  47. Porcine reproductive and respiratory syndrome virus (PRRSV) induces one of most important devastating disease of swine worldwide, and the current methods poorly control it. Previous studies have indicated that...

    Authors: Xibao Shi, Xiaozhuan Zhang, Yongzhe Chang, Bo Jiang, Ruiguang Deng, Aiping Wang and Gaiping Zhang
    Citation: BMC Veterinary Research 2016 12:90
  48. Gastrointestinal and respiratory diseases in calves and piglets lead to significant economic losses in livestock husbandry. A high morbidity has been reported for diarrhea (calves ≤ 35 %; piglets ≤ 50 %) and f...

    Authors: Hannah Ayrle, Meike Mevissen, Martin Kaske, Heiko Nathues, Niels Gruetzner, Matthias Melzig and Michael Walkenhorst
    Citation: BMC Veterinary Research 2016 12:89
  49. Chicken is fast becoming the world’s most consumed meat. As a consequence poultry health is more important now than ever before, with pathogens of chickens recognised as serious threats to food security. One s...

    Authors: Isa D. Jatau, Idris A. Lawal, Jacob K. P. Kwaga, Fiona M. Tomley, Damer P. Blake and Andrew J. Nok
    Citation: BMC Veterinary Research 2016 12:86

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