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BMC Veterinary Research


Section edited by Cheryl London

The oncology section publishes research findings which focus on studies that address the etiology and treatment of cancer in veterinary patients. We consider studies on cancer prevention, therapeutic strategies, molecular diagnostics, genetics and genomics, epidemiology and comparative oncology

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  1. Content type: Research article

    Early signs of canine transitional cell carcinoma (TCC) are frequently assumed to be caused by other lower urinary tract diseases (LUTD) such as urinary tract infections, resulting in late diagnosis of TCC whi...

    Authors: Michael S. Kent, Allison Zwingenberger, Jodi L. Westropp, Laura E. Barrett, Blythe P. Durbin-Johnson, Paramita Ghosh and Ruth L. Vinall

    Citation: BMC Veterinary Research 2017 13:339

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  2. Content type: Research article

    Hyperthermia is an established anti-cancer treatment but is limited by tolerance of adjacent normal tissues. Parenteral administration of gold nanorods (NRs) as a photosensitizer amplifies the effects of hyper...

    Authors: Elizabeth M. Schuh, Roberta Portela, Heather L. Gardner, Christian Schoen and Cheryl A. London

    Citation: BMC Veterinary Research 2017 13:294

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  3. Content type: Case Report

    Canine joint sarcomas, designated synovial sarcomas, are uncommon malignant mesenchymal neoplasms that occur in the large joints of the extremities of middle-aged, large-breed dogs. We report the diagnosis of ...

    Authors: SER Lovell, RK Burchell, PJ Roady, RL Fredrickson and A Gal

    Citation: BMC Veterinary Research 2017 13:247

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  4. Content type: Research article

    The chick embryo chorioallantoic membrane (CAM) model is well described in human medicine as a cost-effective, easy to perform preclinical oncological model for observing pro- and antiangiogenic response, tumo...

    Authors: Katarzyna Zabielska-Koczywąs, Agata Wojtkowska, Izabella Dolka, Anna Małek, Magdalena Walewska, Anna Wojtalewicz, Artur Żbikowski and Roman Lechowski

    Citation: BMC Veterinary Research 2017 13:201

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  5. Content type: Research article

    Osteosarcoma (OSA) is a common malignant bone tumor of large breed dogs that occurs at predictable anatomic sites. At the time of initial diagnosis, most affected dogs have occult pulmonary metastases. Even wi...

    Authors: B. G. Murphy, M. Y. Mok, D. York, R. Rebhun, K. D. Woolard, C. Hillman, P. Dickinson and K. Skorupski

    Citation: BMC Veterinary Research 2017 13:189

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  6. Content type: Research article

    The pathological condition of canine prostate cancer resembles that of human androgen-independent prostate cancer. Both canine and human androgen receptor (AR) signalling are inhibited by overexpression of the...

    Authors: Yuiko Kato, Kazuhiko Ochiai, Shota Kawakami, Nobuhiro Nakao, Daigo Azakami, Makoto Bonkobara, Masaki Michishita, Masami Morimatsu, Masami Watanabe and Toshinori Omi

    Citation: BMC Veterinary Research 2017 13:170

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  7. Content type: Research article

    Ki67 index, tumor associated macrophages (TAMs) and mast cells (MCs) are associated with malignancies in animal and human neoplasms including colorectal carcinomas (CRC). This has not been assessed in canine C...

    Authors: M. Woldemeskel, I. Hawkins and L. Whittington

    Citation: BMC Veterinary Research 2017 13:111

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  8. Content type: Research article

    Cutaneous squamous cell carcinoma of the nasal planum in cats is a common indication for antitumor treatment such as external beam radiation therapy. Curative-intent radiation therapy has been described as a v...

    Authors: Evgeniya Gasymova, Valeria Meier, Franco Guscetti, Simona Cancedda, Malgorzata Roos and Carla Rohrer Bley

    Citation: BMC Veterinary Research 2017 13:86

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  9. Content type: Research article

    Canine mammary tumors represent the most common neoplasm in female dogs, and the discovery of cancer biomarkers and their translation to clinical relevant assays is a key requirement in the war on cancer. Sinc...

    Authors: Giovanni Pietro Burrai, Alessandro Tanca, Tiziana Cubeddu, Marcello Abbondio, Marta Polinas, Maria Filippa Addis and Elisabetta Antuofermo

    Citation: BMC Veterinary Research 2017 13:38

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  10. Content type: Research article

    Canine B-cell lymphoma is deemed an ideal model of human non-Hodgkin’s lymphoma where the lymphomas of both species share similar clinical features and biological behaviors. However there are some differences ...

    Authors: Mohamad Zamani-Ahmadmahmudi, Sina Aghasharif and Keyhan Ilbeigi

    Citation: BMC Veterinary Research 2017 13:17

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  11. Content type: Research article

    The aim of this study was to describe the prevalence and tissue distribution of neoplasms in Italian ferrets, compared to the epidemiological data previously reported in USA and Japan.

    Authors: Giancarlo Avallone, Annalisa Forlani, Marco Tecilla, Elena Riccardi, Sara Belluco, Sara Francesca Santagostino, Guido Grilli, Kiumars Khadivi and Paola Roccabianca

    Citation: BMC Veterinary Research 2016 12:275

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  12. Content type: Research article

    Splenic masses are common in older dogs; yet diagnosis preceding splenectomy and histopathology remains elusive. MicroRNAs (miRNAs) are short, non-coding RNAs that play a role in post-transcriptional regulatio...

    Authors: Janet A. Grimes, Nripesh Prasad, Shawn Levy, Russell Cattley, Stephanie Lindley, Harry W. Boothe, Ralph A. Henderson and Bruce F. Smith

    Citation: BMC Veterinary Research 2016 12:272

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  13. Content type: Research article

    Ultrasonography to visualize adrenal gland lesions and evaluate incidentally discovered adrenal masses in dogs has become more reliable with advances in imaging techniques. However, correlations between sonogr...

    Authors: Elena Pagani, Massimiliano Tursi, Chiara Lorenzi, Alberto Tarducci, Barbara Bruno, Enrico Corrado Borgogno Mondino and Renato Zanatta

    Citation: BMC Veterinary Research 2016 12:267

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  14. Content type: Research article

    Effective therapies for transitional cell carcinoma (TCC) are limited, with objective response rates to most chemotherapeutic regimens below 20%. The purpose of this study was to investigate the biologic activ...

    Authors: Sarah B. Rippy, Heather L. Gardner, Sandra M. Nguyen, Emma E. Warry, Roberta F. Portela, William Tod Drost, Eric T. Hostnik, Eric M. Green, Dennis J. Chew, Juan Peng and Cheryl A. London

    Citation: BMC Veterinary Research 2016 12:257

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    The Erratum to this article has been published in BMC Veterinary Research 2016 12:291

  15. Content type: Case Report

    Lung cancer is the most commonly diagnosed neoplasm in humans, however this does not apply to other animal species. Living in an aquatic environment the respiratory system of cetaceans had to undergo unique ad...

    Authors: Cristian M. Suárez-Santana, Carolina Fernández-Maldonado, Josué Díaz-Delgado, Manuel Arbelo, Alejandro Suárez-Bonnet, Antonio Espinosa de los Monteros, Nakita Câmara, Eva Sierra and Antonio Fernández

    Citation: BMC Veterinary Research 2016 12:229

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  16. Content type: Research article

    Leukemia/lymphoma cell lines have been critical in the investigation of the pathogenesis and therapy of hematological malignancies. While human LL cell lines have generally been found to recapitulate the prima...

    Authors: Sarah C. Roode, Daniel Rotroff, Kristy L. Richards, Peter Moore, Alison Motsinger-Reif, Yasuhiko Okamura, Takuya Mizuno, Hajime Tsujimoto, Steven E. Suter and Matthew Breen

    Citation: BMC Veterinary Research 2016 12:207

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  17. Content type: Research article

    Current studies report that aberrations in epigenetic regulators or chromatin modifications are related to tumor development and maintenance. EZH2 (Enhancer of zeste homolog 2) is one of the catalytic subunits...

    Authors: Hyun-Ji Choi, Sungwoong Jang, Jae-Eun Ryu, Hyo-Ju Lee, Han-Byul Lee, Woo-Sung Ahn, Hye-Jin Kim, Hyo-Jin Lee, Hee Jin Lee, Gyung-Yub Gong and Woo-Chan Son

    Citation: BMC Veterinary Research 2016 12:164

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  18. Content type: Research article

    Adjunctive use of nutraceuticals in human cancer has shown promise, but little work has been done in canine neoplasia. Previous human research has shown that polyphenols and carotenoids can target multiple pat...

    Authors: Corri B. Levine, Julie Bayle, Vincent Biourge and Joseph J. Wakshlag

    Citation: BMC Veterinary Research 2016 12:159

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  19. Content type: Case Report

    Ovarian tumors in reptiles are uncommonly reported in the literature and for green iguanas previously reported cases include teratomas, one adenocarcinoma and one papillary cystadenocarcinoma. The present repo...

    Authors: Lucia Bel, Marco Tecilla, Gabriel Borza, Cosmin Pestean, Robert Purdoiu, Ciprian Ober, Liviu Oana and Marian Taulescu

    Citation: BMC Veterinary Research 2016 12:144

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  20. Content type: Research article

    KIT is a tyrosine kinase growth factor receptor. High expression of KIT has been found in several tumors including canine hemangiosarcoma (HSA). This study investigated the correlation of KIT expression and c-kit

    Authors: Yi-Chen Chen, Jiunn-Wang Liao, Wei-Li Hsu and Shih-Chieh Chang

    Citation: BMC Veterinary Research 2016 12:142

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