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Neurology and neuroscience

Section edited by Prof. Holger Volk

The neurology and neuroscience section combines all aspects of this specialty into a single section, and also includes those aspects of neurology and neurosurgery that overlap with other disciplines, such as internal medicine, surgery, imaging, and pathology. This section encourages high-quality submissions of basic and clinical research on the anatomy, development, and physiology of the nervous system as well as all aspects of clinical neurology, including the development, prevention, diagnosis and treatment of diseases of the central and peripheral nervous system, including muscular diseases. Comparative and translational studies relevant to the central or peripheral nervous system of all domestic and non-domestic species are considered. 
 

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  1. Behavioural changes associated with idiopathic epilepsy (IE) have been identified in dogs, with fear and anxiety-related problems seen in both drug-naïve dogs and dogs treated with anti-epileptic drugs (AEDs)....

    Authors: Rowena M. A. Packer, Luisa De Risio and Holger A. Volk

    Citation: BMC Veterinary Research 2017 13:90

    Content type: Research article

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  2. Cervical spondylomyelopathy (CSM), also known as wobbler syndrome, affects mainly large and giant-breed dogs, causing compression of the cervical spinal cord and/or nerve roots. Structural and dynamic componen...

    Authors: Marília de Albuquerque Bonelli, Ronaldo Casimiro da Costa, Paula Martin-Vaquero and Carolina Gonçalves Dias Lima

    Citation: BMC Veterinary Research 2017 13:77

    Content type: Research article

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  3. Epilepsy is the most common neurological disease in veterinary practice. However, contrary to human medicine, epilepsy classification in veterinary medicine had not been clearly defined until recently. A numbe...

    Authors: Yuji Hamamoto, Daisuke Hasegawa, Shunta Mizoguchi, Yoshihiko Yu, Masae Wada, Takayuki Kuwabara, Aki Fujiwara-Igarashi and Michio Fujita

    Citation: BMC Veterinary Research 2016 12:248

    Content type: Research article

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  4. Canine ventral atlantoaxial (AA) stabilization is most commonly performed in very small dogs and is technically challenging due to extremely narrow bone corridors. Multiple implantation sites have been suggest...

    Authors: Guillaume Leblond, Luis Gaitero, Noel M. Moens, Alex zur Linden, Fiona M. K. James, Gabrielle Monteith and John Runciman

    Citation: BMC Veterinary Research 2016 12:188

    Content type: Methodology article

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  5. Hippocampal necrosis in cats has been reported to be associated with epileptic seizures. Magnetic resonance imaging (MRI) features of temporal lobe (TL) abnormalities in epileptic cats have been described but ...

    Authors: Anne Christine Claßen, Sibylle Kneissl, Johann Lang, Alexander Tichy and Akos Pakozdy

    Citation: BMC Veterinary Research 2016 12:165

    Content type: Research article

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  6. Acute Idiopathic Polyradiculoneuritis, an animal model for the axonal form of the Guillain – Barre Syndrome in humans and the acquired myasthenia gravis are different autoimmune disorders affecting the periphe...

    Authors: Gabriela Dumitrita Stanciu and Gheorghe Solcan

    Citation: BMC Veterinary Research 2016 12:111

    Content type: Case report

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  7. Evaluating beneficial effects of potential protective therapies following cardiac arrest in rodent models could be enhanced by exploring behavior and cognitive functions. The Morris Water Maze is a well-known ...

    Authors: Wolfgang Weihs, Alexandra-M Warenits, Florian Ettl, Ingrid A. M. Magnet, Ursula Teubenbacher, Andreas Hilpold, Andreas Schober, Christoph Testori, Akos Tiboldi, Katharina Tillmann Mag, Michael Holzer, Sandra Hoegler, Andreas Janata and Fritz Sterz

    Citation: BMC Veterinary Research 2016 12:103

    Content type: Research article

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  8. The safety profile of anti-epileptic drugs (AEDs) is an important consideration for the regulatory bodies, owners and prescribing clinicians. Information on their adverse effects still remains limited. A syste...

    Authors: Marios Charalambous, Sara K. Shivapour, David C. Brodbelt and Holger A. Volk

    Citation: BMC Veterinary Research 2016 12:79

    Content type: Research article

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  9. Functional magnetic resonance imaging (fMRI) is an advanced and frequently used technique for studying brain functions in humans and increasingly so in animals. A key element of analyzing fMRI data is group an...

    Authors: Jan-Peter Bach, Matthias Lüpke, Peter Dziallas, Patrick Wefstaedt, Stefan Uppenkamp, Hermann Seifert and Ingo Nolte

    Citation: BMC Veterinary Research 2016 12:32

    Content type: Research article

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  10. Classical scrapie is a transmissible spongiform encephalopathy (TSE) that affects sheep and goats. Our previous bioassay studies in lambs revealed that scrapie prions could be detected in association with peri...

    Authors: Rohana P. Dassanayake, Sally A. Madsen-Bouterse, Thomas C. Truscott, Dongyue Zhuang, Michelle R. Mousel, William C. Davis and David A. Schneider

    Citation: BMC Veterinary Research 2016 12:27

    Content type: Research article

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  11. The purpose of this study was to prove the hypothesis that C-reactive protein (CRP) and nerve growth factor (NGF) may be potential biomarkers for lower urinary tract disorders and may be able to distinguish be...

    Authors: Ulrike Kordass, Regina Carlson, Veronika Maria Stein and Andrea Tipold

    Citation: BMC Veterinary Research 2016 12:7

    Content type: Research article

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  12. [11C]-3-amino-4-(2-dimethylaminomethyl-phenylsulfanyl)-benzonitrile ([11C]DASB) is currently the mostly used radiotracer for positron emission tomography (PET) quantitative studies of the serotonin transporter (S...

    Authors: Olivia Taylor, Nick Van Laeken, Filip De Vos, Ingeborgh Polis, Tim Bosmans, Ingeborg Goethals, Rik Achten, Andre Dobbeleir, Eva Vandermeulen, Chris Baeken, Jimmy Saunders and Kathelijne Peremans

    Citation: BMC Veterinary Research 2015 11:308

    Content type: Research article

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  13. The aims of this field trial were to describe the clinical-pathologic findings in calves with otitis media (OM) and media-interna (OMI), to evaluate, through the development of a scoring system, the effectiven...

    Authors: I. Bertone, C. Bellino, G. L. Alborali, A. Cagnasso, G. Cagnotti, E. Dappiano, M. Lizzi, M. Miciletta, A. Ramacciotti, P. Gianella and A. D’Angelo

    Citation: BMC Veterinary Research 2015 11:297

    Content type: Research article

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  14. An ovine model can cast great insight in translational neuroscientific research due to its large brain volume and distinct regional neuroanatomical structures. The present study examined the applicability of b...

    Authors: Wonhye Lee, Stephanie D. Lee, Michael Y. Park, Lori Foley, Erin Purcell-Estabrook, Hyungmin Kim and Seung-Schik Yoo

    Citation: BMC Veterinary Research 2015 11:262

    Content type: Methodology article

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  15. The objective of this study was to develop and assess the reliability of a modified scoring system for evaluating the function of the two pelvic limbs separately, in ambulatory thoracolumbar myelopathy dogs. A...

    Authors: Chung-Sheng Lee, R. Timothy Bentley, Hsin-Yi Weng and Gert J. Breur

    Citation: BMC Veterinary Research 2015 11:241

    Content type: Research article

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  16. Imepitoin is a novel antiepileptic drug for the treatment of canine idiopathic epilepsy. The present study was conducted to demonstrate superior antiepileptic activity of a high dose of 30 mg/kg BID over a low...

    Authors: Chris Rundfeldt, Andrea Tipold and Wolfgang Löscher

    Citation: BMC Veterinary Research 2015 11:228

    Content type: Research article

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  17. This study describes the ultrasonographic appearance of the atlanto-occipital space and ultrasound-guided collection of cerebrospinal fluid (CSF) in cattle. The atlanto-occipital space of 73 euthanized cattle ...

    Authors: Ueli Braun, Jeannette Attiger and Carina Brammertz

    Citation: BMC Veterinary Research 2015 11:227

    Content type: Research article

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  18. We compared the changes in cell morphology, total and differential cell counts between cerebrospinal fluid (CSF) samples analyzed within an hour of collection (fresh sample) and after the addition of autologou...

    Authors: C. Bellino, B. Miniscalco, I. Bertone, A. Cagnasso, E. Occhiena, P. Gianella and A. D’Angelo

    Citation: BMC Veterinary Research 2015 11:201

    Content type: Research article

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  19. Previous studies in humans have reported that the dimensions of the intervertebral foramina change significantly with movement of the spine. Cervical spondylomyelopathy (CSM) in dogs is characterized by dynami...

    Authors: Renato M. Ramos, Ronaldo C. da Costa, Andre LA Oliveira, Manoj K. Kodigudla and Vijay K. Goel

    Citation: BMC Veterinary Research 2015 11:184

    Content type: Research article

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  20. Various antiepileptic drugs (AEDs) are used for the management of canine idiopathic epilepsy (IE). Information on their clinical efficacy remains limited. A systematic review was designed to evaluate existing ...

    Authors: Marios Charalambous, David Brodbelt and Holger A Volk

    Citation: BMC Veterinary Research 2014 10:257

    Content type: Research article

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  21. Atypical bovine spongiform encephalopathies (BSEs), classified as H-type and L-type BSE based on the Western immunoblot profiles, are naturally occurring diseases in cattle, which are phenotypically different ...

    Authors: Timm Konold, Laura J Phelan, Derek Clifford, Melanie J Chaplin, Saira Cawthraw, Michael J Stack and Marion M Simmons

    Citation: BMC Veterinary Research 2014 10:243

    Content type: Research article

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  22. Anatomical differences between humans and domestic mammals preclude the use of reported stereotactic approaches to the brainstem in animals. In animals, brainstem biopsies are required both for histopathologic...

    Authors: Anne Staudacher, Anna Oevermann, Michael H Stoffel and Daniela Gorgas

    Citation: BMC Veterinary Research 2014 10:216

    Content type: Methodology article

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  23. Chemokines such as MIP-3β/CCL19 are important factors in the mechanism of cell migration and pathogenesis of central nervous system (CNS) inflammatory reactions. The hypothesis of this study is that CCL19, als...

    Authors: Janina Bartels, Brett G Darrow, Scott J Schatzberg, Lijing Bu, Regina Carlson and Andrea Tipold

    Citation: BMC Veterinary Research 2014 10:157

    Content type: Research article

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  24. Cryptococcus spp. are saprophytic and opportunistic fungal pathogens that are known to cause severe disease in immunocompromised animals. In goats there are reports of clinical cryptococcal pneumonia and mastitis...

    Authors: George Stilwell and Hugo Pissarra

    Citation: BMC Veterinary Research 2014 10:84

    Content type: Case report

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  25. An inexpensive method of generating continuous data on hind limb function in dogs with spinal cord injury is needed to facilitate multicentre clinical trials. This study aimed to define normal fore limb, hind ...

    Authors: Natasha J Olby, Ji-Hey Lim, Kellett Babb, Kathleen Bach, Cullen Domaracki, Kim Williams, Emily Griffith, Tonya Harris and Audrey Muguet-Chanoit

    Citation: BMC Veterinary Research 2014 10:58

    Content type: Methodology article

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  26. Dermoid sinus is an uncommon epithelial-lined fistula that may be associated with vertebral malformations. In humans, Klippel-Feil syndrome (KFS) is a rare condition characterized by congenital cervical verteb...

    Authors: Natasha Barrios, Marcelo Gómez, Marcelo Mieres, Frank Vera and Genaro Alvial

    Citation: BMC Veterinary Research 2014 10:54

    Content type: Case report

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  27. Thrombosis has been associated to some diseases like hyperadrenocorticism (HAC). Several drugs can alter the balance, such as the corticosteroid prednisone, used mainly for its anti-inflammatory and immunosupp...

    Authors: Felipe Gazza Romão, Elza Fernanda Campos, Claudio Roberto Scabelo Mattoso and Regina Kiomi Takahira

    Citation: BMC Veterinary Research 2013 9:268

    Content type: Research article

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  28. Epilepsy is one of the most common chronic neurological disorders in dogs characterized by recurrent seizures. The endocannabinoid (EC) system plays a central role in suppressing pathologic neuronal excitabili...

    Authors: Felix K Gesell, Alexander A Zoerner, Christina Brauer, Stefan Engeli, Dimitros Tsikas and Andrea Tipold

    Citation: BMC Veterinary Research 2013 9:262

    Content type: Research article

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  29. Functional magnetic resonance imaging (fMRI) is a technique able to localize neural activity in the brain by detecting associated changes in blood flow. It is an essential tool for studying human functional ne...

    Authors: Jan-Peter Bach, Matthias Lüpke, Peter Dziallas, Patrick Wefstaedt, Stefan Uppenkamp, Hermann Seifert and Ingo Nolte

    Citation: BMC Veterinary Research 2013 9:210

    Content type: Research article

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  30. Mammalian juveniles undergo dramatic changes in body conformation during development. As one of the most common companion animals, the time line and trajectory of a dog’s development and its body’s re-proporti...

    Authors: Daniela Helmsmüller, Patrick Wefstaedt, Ingo Nolte and Nadja Schilling

    Citation: BMC Veterinary Research 2013 9:203

    Content type: Research article

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  31. Eventing is generally recognized as a challenging equestrian discipline and wastage figures for this discipline are relatively high. There is a need for information that provides insight into the causes of was...

    Authors: CarolienCBM Munsters, Jan van den Broek, Emile Welling, René van Weeren and MarianneM Sloet van Oldruitenborgh-Oosterbaan

    Citation: BMC Veterinary Research 2013 9:182

    Content type: Research article

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  32. Tumescent anaesthesia (TA) is a widely used technique in oncologic surgeries necessitating large resection margins. This technique produces transoperative and postoperative analgesia, reduces surgical bleeding...

    Authors: Leonardo de Freitas Guimaraes Arcoverde Credie, Stelio Pacca Loureiro Luna, Fabio Futema, Luciano Cacciari Baruffaldi Almeida da Silva, Giancarlo Bressane Gomes, Jaqueline Neratika Negrette Garcia and Lidia Raquel de Carvalho

    Citation: BMC Veterinary Research 2013 9:178

    Content type: Research article

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  33. Bovine tuberculosis (BTB) and bovine brucellosis are two important milk-borne zoonoses that have been shown to be prevalent to various degrees in Ethiopian cattle.

    Authors: Rea Tschopp, Birhanu Abera, Sabi Yao Sourou, Emmanuelle Guerne-Bleich, Abraham Aseffa, Alehegne Wubete, Jakob Zinsstag and Douglas Young

    Citation: BMC Veterinary Research 2013 9:163

    Content type: Research article

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  34. Lissencephaly is a rare developmental brain disorder in veterinary and human medicine associated with defects in neuronal migration leading to a characteristic marked reduction or absence of the convolutional ...

    Authors: Valentín Pérez, Aroa Suárez-Vega, Miguel Fuertes, Julio Benavides, Laetitia Delgado, M Carmen Ferreras and Juan José Arranz

    Citation: BMC Veterinary Research 2013 9:156

    Content type: Research article

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  35. Several factors may influence kinetic data measurements, including body conformation and body mass. In addition, gender differences in gait pattern have been observed in healthy humans. Therefore, the aim of t...

    Authors: Mirela R Verdugo, Sheila C Rahal, Felipe S Agostinho, Verônica M Govoni, Maria J Mamprim and Frederico OB Monteiro

    Citation: BMC Veterinary Research 2013 9:129

    Content type: Research article

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  36. Corneal ulcers are one of the most common eye problems in the horse and can cause varying degrees of visual impairment. Secondary infection and protease activity causing melting of the corneal stroma are alway...

    Authors: Anna Hellander-Edman, Karim Makdoumi, Jes Mortensen and Björn Ekesten

    Citation: BMC Veterinary Research 2013 9:128

    Content type: Research article

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  37. Handling of common marmoset (Callithrix jacchus) usually requires chemical restraint. Ketamine has been associated with muscle damage in primates, while common marmosets, compared to other primates, additionally ...

    Authors: Jaco Bakker, Joost J Uilenreef, Eva RJ Pelt, Herbert PM Brok, Edmond J Remarque and Jan AM Langermans

    Citation: BMC Veterinary Research 2013 9:113

    Content type: Research article

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  38. Little is known about ethnic, cultural and socioeconomic differences in childhood ownership and attitudes to pets. The objective of this study was to describe the factors associated with living with different ...

    Authors: Carri Westgarth, Lynne M Boddy, Gareth Stratton, Alexander J German, Rosalind M Gaskell, Karen P Coyne, Peter Bundred, Sandra McCune and Susan Dawson

    Citation: BMC Veterinary Research 2013 9:102

    Content type: Research article

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  39. Pregnancy-associated glycoproteins (PAGs) were first described as placental antigens present in the blood serum of the mother soon after implantation. Here, we describe the purification of several pregnancy-as...

    Authors: Olimpia Barbato, Noelita Melo de Sousa, Vittoria Lucia Barile, Claudio Canali and Jean-François Beckers

    Citation: BMC Veterinary Research 2013 9:89

    Content type: Research article

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  40. The aim of this study was to use transmission electron microscopy to describe the ultrastructural characteristics of clots obtained from canine and feline platelet concentrates (PC) that had been activated wit...

    Authors: Raúl F Silva, Jorge U Carmona and Cleuza MF Rezende

    Citation: BMC Veterinary Research 2013 9:77

    Content type: Research article

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  41. Recent new anatomical and histological features of craniocervical junction in dogs and cats were described providing evidence of differences between the carnivore species. No information on these structures in...

    Authors: Marta Kupczynska, Karolina Barszcz, Pawel Janczyk, Michal Wasowicz and Norbert Czubaj

    Citation: BMC Veterinary Research 2013 9:64

    Content type: Research article

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  42. The tissue growth necessary to achieve a complete or partial restitution ad integrum as a result of injury to soft tissue and/or hard times in reptiles is variable and often needs long time in relation to the ...

    Authors: Salvatore Rinaldi, Maddalena Iannaccone, Gian Enrico Magi, Emanuela Costantini, Alessandro Castagna, Eraldo Sanna Passino, Margherita Maioli and Vania Fontani

    Citation: BMC Veterinary Research 2013 9:39

    Content type: Case report

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  43. Laterality defects are rare in cattle and usually manifest as asplenia orpolysplenia syndrome. These syndromes may be associated with situs ambiguus,which is a dislocation of some but not all internal organs. ...

    Authors: Alois Boos, Hans Geyer, Urs Müller, Jeanne Peter, Tanja Schmid, Christian Gerspach, Matteo Previtali, Maja Rütten, Titus Sydler, Colin C Schwarzwald, Elisabeth M Schraner and Ueli Braun

    Citation: BMC Veterinary Research 2013 9:34

    Content type: Case report

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  44. Steroid Responsive Meningitis-Arteritis (SRMA) is a common cause of inflammation of the canine central nervous system (CNS). To investigate if transforming growth factor beta 1 (TGF-β1), interleukin-6 (IL-6) and ...

    Authors: Arianna Maiolini, Meike Otten, Marion Hewicker-Trautwein, Regina Carlson and Andrea Tipold

    Citation: BMC Veterinary Research 2013 9:23

    Content type: Research article

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  45. Anaesthesia in rabbits is associated with a high mortality rate, compared to that in cats and dogs. Total intravenous anaesthesia (TIVA) with drugs that provide cardiovascular stability and are rapidly metabol...

    Authors: Patricia Hedenqvist, Anna Edner, Åsa Fahlman and Marianne Jensen-Waern

    Citation: BMC Veterinary Research 2013 9:21

    Content type: Research article

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  46. The Maedi-Visna (MV) lentivirus causes two slowly progressive eventually fatal diseases of sheep, Maedi, a progressive interstitial pneumonia, and Visna, a progressive demyelinating disease of the central nerv...

    Authors: Margrét Gudnadóttir, Andreas Demosthenous and Theophanis Hadjisavvas

    Citation: BMC Veterinary Research 2013 9:16

    Content type: Research article

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  47. Swine influenza (SI) is an acute respiratory disease caused by swine influenza virus (SIV). Swine influenza is generally characterized by acute onset of fever and respiratory symptoms. The most frequent compli...

    Authors: Małgorzata Pomorska-Mól, Iwona Markowska-Daniel, Krzysztof Kwit, Katarzyna Stępniewska and Zygmunt Pejsak

    Citation: BMC Veterinary Research 2013 9:14

    Content type: Research article

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As a result of the significant disruption that is being caused by the COVID-19 pandemic we are very aware that many researchers will have difficulty in meeting the timelines associated with our peer review process during normal times.  Please do let us know if you need additional time. Our systems will continue to remind you of the original timelines but we intend to be highly flexible at this time. Thank you.

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