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Neurology and neuroscience

Section edited by Prof. Holger Volk

The neurology and neuroscience section combines all aspects of this specialty into a single section, and also includes those aspects of neurology and neurosurgery that overlap with other disciplines, such as internal medicine, surgery, imaging, and pathology. This section encourages high-quality submissions of basic and clinical research on the anatomy, development, and physiology of the nervous system as well as all aspects of clinical neurology, including the development, prevention, diagnosis and treatment of diseases of the central and peripheral nervous system, including muscular diseases. Comparative and translational studies relevant to the central or peripheral nervous system of all domestic and non-domestic species are considered. 

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  1. Content type: Research article

    The objective of this study was to develop and assess the reliability of a modified scoring system for evaluating the function of the two pelvic limbs separately, in ambulatory thoracolumbar myelopathy dogs. A...

    Authors: Chung-Sheng Lee, R. Timothy Bentley, Hsin-Yi Weng and Gert J. Breur

    Citation: BMC Veterinary Research 2015 11:241

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  2. Content type: Research article

    Imepitoin is a novel antiepileptic drug for the treatment of canine idiopathic epilepsy. The present study was conducted to demonstrate superior antiepileptic activity of a high dose of 30 mg/kg BID over a low...

    Authors: Chris Rundfeldt, Andrea Tipold and Wolfgang Löscher

    Citation: BMC Veterinary Research 2015 11:228

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  3. Content type: Research article

    This study describes the ultrasonographic appearance of the atlanto-occipital space and ultrasound-guided collection of cerebrospinal fluid (CSF) in cattle. The atlanto-occipital space of 73 euthanized cattle ...

    Authors: Ueli Braun, Jeannette Attiger and Carina Brammertz

    Citation: BMC Veterinary Research 2015 11:227

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  4. Content type: Research article

    We compared the changes in cell morphology, total and differential cell counts between cerebrospinal fluid (CSF) samples analyzed within an hour of collection (fresh sample) and after the addition of autologou...

    Authors: C. Bellino, B. Miniscalco, I. Bertone, A. Cagnasso, E. Occhiena, P. Gianella and A. D’Angelo

    Citation: BMC Veterinary Research 2015 11:201

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  5. Content type: Research article

    Previous studies in humans have reported that the dimensions of the intervertebral foramina change significantly with movement of the spine. Cervical spondylomyelopathy (CSM) in dogs is characterized by dynami...

    Authors: Renato M. Ramos, Ronaldo C. da Costa, Andre LA Oliveira, Manoj K. Kodigudla and Vijay K. Goel

    Citation: BMC Veterinary Research 2015 11:184

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  6. Content type: Research article

    Various antiepileptic drugs (AEDs) are used for the management of canine idiopathic epilepsy (IE). Information on their clinical efficacy remains limited. A systematic review was designed to evaluate existing ...

    Authors: Marios Charalambous, David Brodbelt and Holger A Volk

    Citation: BMC Veterinary Research 2014 10:257

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  7. Content type: Research article

    Atypical bovine spongiform encephalopathies (BSEs), classified as H-type and L-type BSE based on the Western immunoblot profiles, are naturally occurring diseases in cattle, which are phenotypically different ...

    Authors: Timm Konold, Laura J Phelan, Derek Clifford, Melanie J Chaplin, Saira Cawthraw, Michael J Stack and Marion M Simmons

    Citation: BMC Veterinary Research 2014 10:243

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  8. Content type: Methodology article

    Anatomical differences between humans and domestic mammals preclude the use of reported stereotactic approaches to the brainstem in animals. In animals, brainstem biopsies are required both for histopathologic...

    Authors: Anne Staudacher, Anna Oevermann, Michael H Stoffel and Daniela Gorgas

    Citation: BMC Veterinary Research 2014 10:216

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  9. Content type: Research article

    Chemokines such as MIP-3β/CCL19 are important factors in the mechanism of cell migration and pathogenesis of central nervous system (CNS) inflammatory reactions. The hypothesis of this study is that CCL19, als...

    Authors: Janina Bartels, Brett G Darrow, Scott J Schatzberg, Lijing Bu, Regina Carlson and Andrea Tipold

    Citation: BMC Veterinary Research 2014 10:157

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  10. Content type: Case report

    Cryptococcus spp. are saprophytic and opportunistic fungal pathogens that are known to cause severe disease in immunocompromised animals. In goats there are reports of clinical cryptococcal pneumonia and mastitis...

    Authors: George Stilwell and Hugo Pissarra

    Citation: BMC Veterinary Research 2014 10:84

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  11. Content type: Methodology article

    An inexpensive method of generating continuous data on hind limb function in dogs with spinal cord injury is needed to facilitate multicentre clinical trials. This study aimed to define normal fore limb, hind ...

    Authors: Natasha J Olby, Ji-Hey Lim, Kellett Babb, Kathleen Bach, Cullen Domaracki, Kim Williams, Emily Griffith, Tonya Harris and Audrey Muguet-Chanoit

    Citation: BMC Veterinary Research 2014 10:58

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  12. Content type: Case report

    Dermoid sinus is an uncommon epithelial-lined fistula that may be associated with vertebral malformations. In humans, Klippel-Feil syndrome (KFS) is a rare condition characterized by congenital cervical verteb...

    Authors: Natasha Barrios, Marcelo Gómez, Marcelo Mieres, Frank Vera and Genaro Alvial

    Citation: BMC Veterinary Research 2014 10:54

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  13. Content type: Research article

    Thrombosis has been associated to some diseases like hyperadrenocorticism (HAC). Several drugs can alter the balance, such as the corticosteroid prednisone, used mainly for its anti-inflammatory and immunosupp...

    Authors: Felipe Gazza Romão, Elza Fernanda Campos, Claudio Roberto Scabelo Mattoso and Regina Kiomi Takahira

    Citation: BMC Veterinary Research 2013 9:268

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  14. Content type: Research article

    Epilepsy is one of the most common chronic neurological disorders in dogs characterized by recurrent seizures. The endocannabinoid (EC) system plays a central role in suppressing pathologic neuronal excitabili...

    Authors: Felix K Gesell, Alexander A Zoerner, Christina Brauer, Stefan Engeli, Dimitros Tsikas and Andrea Tipold

    Citation: BMC Veterinary Research 2013 9:262

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  15. Content type: Research article

    Functional magnetic resonance imaging (fMRI) is a technique able to localize neural activity in the brain by detecting associated changes in blood flow. It is an essential tool for studying human functional ne...

    Authors: Jan-Peter Bach, Matthias Lüpke, Peter Dziallas, Patrick Wefstaedt, Stefan Uppenkamp, Hermann Seifert and Ingo Nolte

    Citation: BMC Veterinary Research 2013 9:210

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  16. Content type: Research article

    Mammalian juveniles undergo dramatic changes in body conformation during development. As one of the most common companion animals, the time line and trajectory of a dog’s development and its body’s re-proporti...

    Authors: Daniela Helmsmüller, Patrick Wefstaedt, Ingo Nolte and Nadja Schilling

    Citation: BMC Veterinary Research 2013 9:203

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  17. Content type: Research article

    Eventing is generally recognized as a challenging equestrian discipline and wastage figures for this discipline are relatively high. There is a need for information that provides insight into the causes of was...

    Authors: CarolienCBM Munsters, Jan van den Broek, Emile Welling, René van Weeren and MarianneM Sloet van Oldruitenborgh-Oosterbaan

    Citation: BMC Veterinary Research 2013 9:182

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  18. Content type: Research article

    Tumescent anaesthesia (TA) is a widely used technique in oncologic surgeries necessitating large resection margins. This technique produces transoperative and postoperative analgesia, reduces surgical bleeding...

    Authors: Leonardo de Freitas Guimaraes Arcoverde Credie, Stelio Pacca Loureiro Luna, Fabio Futema, Luciano Cacciari Baruffaldi Almeida da Silva, Giancarlo Bressane Gomes, Jaqueline Neratika Negrette Garcia and Lidia Raquel de Carvalho

    Citation: BMC Veterinary Research 2013 9:178

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  19. Content type: Research article

    Bovine tuberculosis (BTB) and bovine brucellosis are two important milk-borne zoonoses that have been shown to be prevalent to various degrees in Ethiopian cattle.

    Authors: Rea Tschopp, Birhanu Abera, Sabi Yao Sourou, Emmanuelle Guerne-Bleich, Abraham Aseffa, Alehegne Wubete, Jakob Zinsstag and Douglas Young

    Citation: BMC Veterinary Research 2013 9:163

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  20. Content type: Research article

    Lissencephaly is a rare developmental brain disorder in veterinary and human medicine associated with defects in neuronal migration leading to a characteristic marked reduction or absence of the convolutional ...

    Authors: Valentín Pérez, Aroa Suárez-Vega, Miguel Fuertes, Julio Benavides, Laetitia Delgado, M Carmen Ferreras and Juan José Arranz

    Citation: BMC Veterinary Research 2013 9:156

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  21. Content type: Research article

    Several factors may influence kinetic data measurements, including body conformation and body mass. In addition, gender differences in gait pattern have been observed in healthy humans. Therefore, the aim of t...

    Authors: Mirela R Verdugo, Sheila C Rahal, Felipe S Agostinho, Verônica M Govoni, Maria J Mamprim and Frederico OB Monteiro

    Citation: BMC Veterinary Research 2013 9:129

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  22. Content type: Research article

    Corneal ulcers are one of the most common eye problems in the horse and can cause varying degrees of visual impairment. Secondary infection and protease activity causing melting of the corneal stroma are alway...

    Authors: Anna Hellander-Edman, Karim Makdoumi, Jes Mortensen and Björn Ekesten

    Citation: BMC Veterinary Research 2013 9:128

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  23. Content type: Research article

    Handling of common marmoset (Callithrix jacchus) usually requires chemical restraint. Ketamine has been associated with muscle damage in primates, while common marmosets, compared to other primates, additionally ...

    Authors: Jaco Bakker, Joost J Uilenreef, Eva RJ Pelt, Herbert PM Brok, Edmond J Remarque and Jan AM Langermans

    Citation: BMC Veterinary Research 2013 9:113

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  24. Content type: Research article

    Little is known about ethnic, cultural and socioeconomic differences in childhood ownership and attitudes to pets. The objective of this study was to describe the factors associated with living with different ...

    Authors: Carri Westgarth, Lynne M Boddy, Gareth Stratton, Alexander J German, Rosalind M Gaskell, Karen P Coyne, Peter Bundred, Sandra McCune and Susan Dawson

    Citation: BMC Veterinary Research 2013 9:102

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  25. Content type: Research article

    Pregnancy-associated glycoproteins (PAGs) were first described as placental antigens present in the blood serum of the mother soon after implantation. Here, we describe the purification of several pregnancy-as...

    Authors: Olimpia Barbato, Noelita Melo de Sousa, Vittoria Lucia Barile, Claudio Canali and Jean-François Beckers

    Citation: BMC Veterinary Research 2013 9:89

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  26. Content type: Research article

    The aim of this study was to use transmission electron microscopy to describe the ultrastructural characteristics of clots obtained from canine and feline platelet concentrates (PC) that had been activated wit...

    Authors: Raúl F Silva, Jorge U Carmona and Cleuza MF Rezende

    Citation: BMC Veterinary Research 2013 9:77

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  27. Content type: Research article

    Recent new anatomical and histological features of craniocervical junction in dogs and cats were described providing evidence of differences between the carnivore species. No information on these structures in...

    Authors: Marta Kupczynska, Karolina Barszcz, Pawel Janczyk, Michal Wasowicz and Norbert Czubaj

    Citation: BMC Veterinary Research 2013 9:64

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  28. Content type: Case report

    The tissue growth necessary to achieve a complete or partial restitution ad integrum as a result of injury to soft tissue and/or hard times in reptiles is variable and often needs long time in relation to the ...

    Authors: Salvatore Rinaldi, Maddalena Iannaccone, Gian Enrico Magi, Emanuela Costantini, Alessandro Castagna, Eraldo Sanna Passino, Margherita Maioli and Vania Fontani

    Citation: BMC Veterinary Research 2013 9:39

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  29. Content type: Case report

    Laterality defects are rare in cattle and usually manifest as asplenia orpolysplenia syndrome. These syndromes may be associated with situs ambiguus,which is a dislocation of some but not all internal organs. ...

    Authors: Alois Boos, Hans Geyer, Urs Müller, Jeanne Peter, Tanja Schmid, Christian Gerspach, Matteo Previtali, Maja Rütten, Titus Sydler, Colin C Schwarzwald, Elisabeth M Schraner and Ueli Braun

    Citation: BMC Veterinary Research 2013 9:34

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  30. Content type: Research article

    Steroid Responsive Meningitis-Arteritis (SRMA) is a common cause of inflammation of the canine central nervous system (CNS). To investigate if transforming growth factor beta 1 (TGF-β1), interleukin-6 (IL-6) and ...

    Authors: Arianna Maiolini, Meike Otten, Marion Hewicker-Trautwein, Regina Carlson and Andrea Tipold

    Citation: BMC Veterinary Research 2013 9:23

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  31. Content type: Research article

    Anaesthesia in rabbits is associated with a high mortality rate, compared to that in cats and dogs. Total intravenous anaesthesia (TIVA) with drugs that provide cardiovascular stability and are rapidly metabol...

    Authors: Patricia Hedenqvist, Anna Edner, Åsa Fahlman and Marianne Jensen-Waern

    Citation: BMC Veterinary Research 2013 9:21

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  32. Content type: Research article

    The Maedi-Visna (MV) lentivirus causes two slowly progressive eventually fatal diseases of sheep, Maedi, a progressive interstitial pneumonia, and Visna, a progressive demyelinating disease of the central nerv...

    Authors: Margrét Gudnadóttir, Andreas Demosthenous and Theophanis Hadjisavvas

    Citation: BMC Veterinary Research 2013 9:16

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  33. Content type: Research article

    Swine influenza (SI) is an acute respiratory disease caused by swine influenza virus (SIV). Swine influenza is generally characterized by acute onset of fever and respiratory symptoms. The most frequent compli...

    Authors: Małgorzata Pomorska-Mól, Iwona Markowska-Daniel, Krzysztof Kwit, Katarzyna Stępniewska and Zygmunt Pejsak

    Citation: BMC Veterinary Research 2013 9:14

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  34. Content type: Research article

    The aim of the study was to evaluate the performance of contact heat thermal stimulation in horses at different body sites and under different environmental conditions and different test situations. Five warm-...

    Authors: Christin Poller, Klaus Hopster, Karl Rohn and Sabine BR Kästner

    Citation: BMC Veterinary Research 2013 9:4

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  35. Content type: Research article

    Stereotypic behaviours, i.e. repetitive behaviours induced by frustration, repeated attempts to cope and/or brain dysfunction, are intriguing as they occur in a variety of domestic and captive species without any...

    Authors: Carole Fureix, Haïfa Benhajali, Séverine Henry, Anaelle Bruchet, Armelle Prunier, Mohammed Ezzaouia, Caroline Coste, Martine Hausberger, Rupert Palme and Patrick Jego

    Citation: BMC Veterinary Research 2013 9:3

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  36. Content type: Research article

    Although several histopathological and clinical features of canine mammary gland tumours have been widely studied from a prognostic standpoint, considerable variations in tumour individual biologic behaviour d...

    Authors: Andreia A Santos, Célia C Lopes, Jorge R Ribeiro, Liliana R Martins, Joana C Santos, Irina F Amorim, Fátima Gärtner and Augusto J Matos

    Citation: BMC Veterinary Research 2013 9:1

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  37. Content type: Research article

    The aim of the present prospective study was to investigate whether a decision tree based on basic clinical signs could be used to determine the treatment of metabolic acidosis in calves successfully without e...

    Authors: Florian M Trefz, Annette Lorch, Melanie Feist, Carola Sauter-Louis and Ingrid Lorenz

    Citation: BMC Veterinary Research 2012 8:238

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  38. Content type: Research article

    Mass vaccinations of domestic dogs have been shown to effectively control canine rabies and hence human exposure to rabies. Knowledge of dog population demography is essential for planning effective rabies vac...

    Authors: Alena S Gsell, Darryn L Knobel, Sarah Cleaveland, Rudovick R Kazwala, Penelope Vounatsou and Jakob Zinsstag

    Citation: BMC Veterinary Research 2012 8:236

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  39. Content type: Research article

    This study aimed at determining the extent of tick infestations in extensively grazed cattle and assess the efficacy of Ecotix® acaricide (2.5% high cis cypermethrin) in Mvomero district in Tanzania. A total of 1...

    Authors: Nonga Hezron E, Muwonge Adrian and Mdegela Robinson H

    Citation: BMC Veterinary Research 2012 8:224

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  40. Content type: Research article

    Erythrocyte pyruvate kinase deficiency (PK deficiency) is an inherited hemolytic anemia that has been documented in the Abyssinian and Somali breeds as well as random bred domestic shorthair cats. The disease ...

    Authors: Robert A Grahn, Jennifer C Grahn, Maria CT Penedo, Chris R Helps and Leslie A Lyons

    Citation: BMC Veterinary Research 2012 8:207

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  41. Content type: Methodology article

    In this methodology article a thermal threshold testing device designed to test nociception in cats was assessed in six dogs. The purpose of this study was to investigate baseline reproducibility of thermal th...

    Authors: Marina Verena Hoffmann, Sabine Beate Rita Kästner, Manfred Kietzmann and Sabine Kramer

    Citation: BMC Veterinary Research 2012 8:206

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  42. Content type: Research article

    While emerging diseases are affecting many populations of amphibians, some populations are resistant. Determining the relative contributions of factors influencing disease resistance is critical for effective ...

    Authors: Douglas C Woodhams, Laurent Bigler and Rachel Marschang

    Citation: BMC Veterinary Research 2012 8:197

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  43. Content type: Research article

    Pulsed wave (PW) Doppler echocardiography has become a routine non invasive cardiac diagnostic tool in most species. However, evaluation of intracardiac blood flow requires reference values, which are poorly d...

    Authors: Aurélia A Leroux, Frédéric Farnir, Marie L Moonen, Charlotte F Sandersen, Stefan Deleuze and Hélène Amory

    Citation: BMC Veterinary Research 2012 8:190

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  44. Content type: Research article

    More and more countries hold databases on cattle movements. The primary purpose of the registration of cattle movements is to provide data for quick tracing of contagious animals in case of disease outbreaks a...

    Authors: Henriëtte Brouwer, Chris J M Bartels, Arjan Stegeman and Gerdien van Schaik

    Citation: BMC Veterinary Research 2012 8:188

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  45. Content type: Research article

    Recent studies reported on the very complex morphology of the pulp system in equine cheek teeth. The continuous production of secondary dentine leads to distinct age-related changes of the endodontic cavity. D...

    Authors: Susan Kopke, Nina Angrisani and Carsten Staszyk

    Citation: BMC Veterinary Research 2012 8:173

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  46. Content type: Research article

    One of the purposes of treatment for dogs with mitral regurgitation (MR) is lowering left atrial pressure (LAP). There has been few study of the amlodipine in dogs with MR and amlodipine’s effect on LAP has no...

    Authors: Shuji Suzuki, Ryuji Fukushima, Taisuke Ishikawa, Yuta Yamamoto, Lina Hamabe, Soomin Kim, Rieko Yoshiyuki, Noboru Machida and Ryou Tanaka

    Citation: BMC Veterinary Research 2012 8:166

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