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Gastroenterology and nutrition

Section edited by Dr. Hayley Henderson and Tillie Cryer

The gastroenterology and nutrition section encompasses the broader aspects of animal nutrition, including the processes of digestion, absorption, and metabolism of nutrients at all biological levels, ranging from the molecular, cellular, tissue and organ level to clinical studies. The section welcomes submissions discussing the provision and ingestion of food vital to development, growth and overall health. As the digestive tract is considered to be one of the most important immune organs and adipose tissue is the biggest endocrine organ, manuscripts that focus on the relationship between immunology and endocrinology are especially welcome. Studies that advance our understanding of the nutritional status of animals and the role of nutrition in the onset of disease are also encouraged. Comparative nutrition and nutritional studies relevant to all domestic and nondomestic species will be considered, including ruminants, equids, companion animals, and laboratory animals. 

This section also encourages submissions describing emerging research areas, such as the effects of foods and food constituents on gene expression, nutrigenomics, and the effects of genetic variation on the absorption, metabolism, elimination, and biological outcomes of nutrients. Other specific topics of interest include food, malnutrition, vitamin deficiency, rumen fermentation, restricted feeding, inflammation, metabolic disorders, lifestyle-related illnesses (obesity, metabolic syndrome, diabetes, and hypertension), neoplasia, genetic diagnosis, and the development of supplements and drugs in animals.

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  1. Content type: Research article

    Cysteamine was coated to cover its odor and maintain the stability. However, coated cysteamine (CC) has not been clearly evaluated for its effects on the gastrointestinal mucosa status. We hypothesize that the...

    Authors: Hongnan Liu, Miaomiao Bai, Bie Tan, Kang Xu, Rong Yu, Ruilin Huang and Yulong Yin

    Citation: BMC Veterinary Research 2019 15:328

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  2. Content type: Research article

    Postbiotics have been established as potential feed additive to be used in monogastric such as poultry and swine to enhance health and growth performance. However, information on the postbiotics as feed additi...

    Authors: Wan Ibrahim Izuddin, Teck Chwen Loh, Anjas Asmara Samsudin, Hooi Ling Foo, Ali Merzza Humam and Nurhazirah Shazali

    Citation: BMC Veterinary Research 2019 15:315

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  3. Content type: Research article

    Magnetic resonance imaging using gadoxetic acid, a hepatocyte-specific contrast agent, is one of the most useful MRI techniques used to diagnose liver tumours in humans. During the hepato-biliary phase, there ...

    Authors: Pola Borusewicz, Ewa Stańczyk, Krzysztof Kubiak, Jolanta Spużak, Kamila Glińska-Suchocka, Marcin Jankowski, Piotr Sławuta, Dominika Kubiak-Nowak and Przemysław Podgórski

    Citation: BMC Veterinary Research 2019 15:293

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  4. Content type: Research article

    Osteoarthritis is a common canine disease frequently treated with nutritional supplements that often lack independent verification of ingredients, active ingredient concentration, efficacy, or safety. Human su...

    Authors: Erin Miscioscia, Justin Shmalberg and Karen C. Scott

    Citation: BMC Veterinary Research 2019 15:270

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  5. Content type: Research article

    In practical production, dairy cows are frequently exposed to bacterial endotoxin (lipopolysaccharide, LPS) when they are subjected to high-concentrate diets, poor hygienic environments, as well as mastitis an...

    Authors: Jingbo Chen, Yongjiang Wu, Yawang Sun, Xianwen Dong, Zili Wang, Zhu Zhang, Yanli Xiao and Guozhong Dong

    Citation: BMC Veterinary Research 2019 15:267

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  6. Content type: Research article

    Gastrointestinal microbiota play an important role in animal host immunity, nutrient metabolism, and energy acquisition, and have therefore drawn increasing attentions. This study compared the diversity of the...

    Authors: Xiangwen Chi, Hongmei Gao, Guosheng Wu, Wen Qin, Pengfei Song, Lei Wang, Jiarui Chen, Zhenyuan Cai and Tongzuo Zhang

    Citation: BMC Veterinary Research 2019 15:243

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  7. Content type: Research article

    Probiotics are important for pigs to enhance health and intestinal development, which are potential alternative to antibiotics. Many studies have reported the functions of single bacterial strain as probiotic ...

    Authors: Shilan Wang, Bingqian Yao, Hang Gao, Jianjun Zang, Shiyu Tao, Shuai Zhang, Shimeng Huang, Beibei He and Junjun Wang

    Citation: BMC Veterinary Research 2019 15:239

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  8. Content type: Research article

    Enterotoxigenic Escherichia coli K88 (E. coli K88) are considered as a major cause of diarrhea and death in newly weaned piglets. Oral passive immunization with chicken egg yolk immunoglobulins (IgY) have attract...

    Authors: Zhaobin Wang, Jia Li, Jianzhong Li, Yali Li, Lixia Wang, Qingping Wang, Lin Fang, Xueqin Ding, Pengfei Huang, Jia Yin, Yulong Yin and Huansheng Yang

    Citation: BMC Veterinary Research 2019 15:234

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  9. Content type: Research article

    The increasing costs of feed has subsequently increased the costs of production of livestock, thereby decreasing the profit margin of this sector. The utilization of agro-industrial by-products has to some ext...

    Authors: O. A. Saeed, A. Q. Sazili, H. Akit, M. Ebrahimi, A. R. Alimon and A. A. Samsudin

    Citation: BMC Veterinary Research 2019 15:233

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  10. Content type: Research article

    Leptin has been shown to have various physiological and pathological roles in the canine gallbladder. In this study, we performed pre- and postoperative short-term follow-up analyses to confirm changes in seru...

    Authors: Sungin Lee, Aeri Lee, Oh-kyeong Kweon and Wan Hee Kim

    Citation: BMC Veterinary Research 2019 15:215

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  11. Content type: Research article

    The purpose of the present study was to assess if the exposure to glutamine (Gln), arginine (Arg) or their combination from pregnancy, through the maternal diet, to a post weaning supplemented diet, can stimul...

    Authors: Rebeca Delgado, Rodrigo Abad-Guamán, Nuria Nicodemus, Araceli Diaz-Perales, Javier García, Rosa Carabaño and David Menoyo

    Citation: BMC Veterinary Research 2019 15:199

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  12. Content type: Research article

    Ex vivo whole blood stimulation assays (WBSA) have been used to characterize the cytokine response to diet in cats. The present study aimed to use this assay to determine the cytokine response to diets being f...

    Authors: Aarti Kathrani and Edward Hall

    Citation: BMC Veterinary Research 2019 15:185

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  13. Content type: Research article

    Obesity in dogs is an increasing problem associated with morbidity, shortened life span and poor life quality. Overweight dogs exhibit postprandial hyperlipidaemia, highlighting the need to identify potential ...

    Authors: Josefin Söder, Sara Wernersson, Johan Dicksved, Ragnvi Hagman, Johnny R. Östman, Ali A. Moazzami and Katja Höglund

    Citation: BMC Veterinary Research 2019 15:96

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  14. Content type: Research article

    The popularity of raw meat-based diets (RMBDs) for pets has been increasing in recent years even if the reputed health benefits are mainly anecdotal. A web-based survey was developed to better understand the m...

    Authors: Giada Morelli, Sofia Bastianello, Paolo Catellani and Rebecca Ricci

    Citation: BMC Veterinary Research 2019 15:74

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  15. Content type: Research article

    Antibiotics (AB) are an important tool to tackle infectious disease in pig farms; however some research indicates that their frequent mis/over-use may contribute to the development of antibiotic resistance and...

    Authors: Alessia Diana, Laura A. Boyle, Finola C. Leonard, Ciaran Carroll, Eugene Sheehan, Declan Murphy and Edgar G. Manzanilla

    Citation: BMC Veterinary Research 2019 15:67

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  16. Content type: Research article

    The first month of life possess significant challenges for dairy calves due to high susceptibility to digestive diseases. The objective of this study was to evaluate the effect of prebiotic supplementation wit...

    Authors: Ana Velasquez-Munoz, Diego Manriquez, Sushil Paudyal, Hyungchul Han, Robert Callan, Elizabeth P. Ryan and Pablo Pinedo

    Citation: BMC Veterinary Research 2019 15:53

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  17. Content type: Research article

    Infection of the digestive track by gastro-intestinal pathogens results in the development of symptoms ranging from mild diarrhea to more severe clinical signs such as dysentery, severe dehydration and potenti...

    Authors: Caroline Ivanne Le Roy, Martin John Woodward, Richard John Ellis, Roberto Marcello La Ragione and Sandrine Paule Claus

    Citation: BMC Veterinary Research 2019 15:37

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  18. Content type: Methodology article

    Computed tomography (CT) has been used to estimate body composition and determine tissue distribution in dogs, despite limited validation. This may introduce error into estimates of body composition studies an...

    Authors: R. B. S. Turner, G. Hepworth, K. Wilson, D. Tyrrell, F. R. Dunshea and C. S. Mansfield

    Citation: BMC Veterinary Research 2019 15:21

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  19. Content type: Case Report

    Successful clinical outcomes of faecal microbiota transplantation (FMT) for recurrent Clostridium difficile infection have been reported in humans and a marmoset. However, it has been unclear whether oral FMT was...

    Authors: Koji Sugita, Nanako Yanuma, Hikaru Ohno, Kaho Takahashi, Koji Kawano, Hidetoshi Morita and Keitaro Ohmori

    Citation: BMC Veterinary Research 2019 15:11

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  20. Content type: Research article

    Overfeeding of high-concentrate diet (HC) frequently leads to subacute ruminal acidosis (SARA) in modern dairy cows’ production. Thiamine supplementation has been confirmed to attenuate HC induced SARA by incr...

    Authors: Fuguang Xue, Xuemei Nan, Yunlei Li, Xiaohua Pan, Yuming Guo, Linshu Jiang and Benhai Xiong

    Citation: BMC Veterinary Research 2019 15:7

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  21. Content type: Research article

    High-grain diets that meet the energy requirements of high-producing ruminants are associated with a high risk of rumen disorders. Mild acid treatment with lactic acid (LA) has been used to modify the degradab...

    Authors: You Yang, Guozhong Dong, Zhi Wang, Junhui Liu, Jingbo Chen and Zhu Zhang

    Citation: BMC Veterinary Research 2018 14:408

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  22. Content type: Review

    Commercially produced chickens have become key food-producing animals in the global food system. The scale of production in industrial settings has changed management systems to a point now very far from tradi...

    Authors: M. Siwek, A. Slawinska, K. Stadnicka, J. Bogucka, A. Dunislawska and M. Bednarczyk

    Citation: BMC Veterinary Research 2018 14:402

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  23. Content type: Research article

    The most common approach for controlled weight loss in cats is dietary caloric restriction, using a purpose-formulated diet. Most previous studies have only assessed short-term outcomes, and no previous study ...

    Authors: Erin M. O’Connell, Maria Williams, Shelley L. Holden, Vincent Biourge and Alexander J. German

    Citation: BMC Veterinary Research 2018 14:397

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  24. Content type: Research article

    Gut health in poultry depends on the balance between the host, intestinal microbiota, intestinal microscopic features and diet. The effects of insect meal (a promising alternative protein source for poultry fe...

    Authors: Ilaria Biasato, Ilario Ferrocino, Elena Biasibetti, Elena Grego, Sihem Dabbou, Alessandra Sereno, Francesco Gai, Laura Gasco, Achille Schiavone, Luca Cocolin and Maria Teresa Capucchio

    Citation: BMC Veterinary Research 2018 14:383

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  25. Content type: Research article

    The gastrointestinal tracts of animals are home to large, complex communities of microbes. The compositions of these communities ultimately reflect the coevolution of microorganisms with their animal host and ...

    Authors: Fengping He, Dan Liu, Le Zhang, Jiancheng Zhai, Yue Ma, Yanchun Xu, Guangshun Jiang, Ke Rong and Jianzhang Ma

    Citation: BMC Veterinary Research 2018 14:379

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  26. Content type: Research article

    The effect of soybean hull feeding on the disruption of colonic epithelium barrier function was investigated in goats fed a high-concentrate diet. Twenty-one Boer goats (live weight, 32.57 ± 2.26 kg; age, 1 ye...

    Authors: Kai Zhang, Yuanlu Tu, Lipeng Gao, Meijuan Meng and Yunfeng Bai

    Citation: BMC Veterinary Research 2018 14:376

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  27. Content type: Research article

    Assuming that part of Methionine (Met) is converted into Cystine (Cys), but ignoring the rates with which such phenomenon occurs may lead to an excessive supply of Met in poultry diets. Such inconvenient could...

    Authors: Letícia G. Pacheco, Nilva K. Sakomura, Rafael M. Suzuki, Juliano C. P. Dorigam, Gabriel S. Viana, Jaap Van Milgen and Juliana C. Denadai

    Citation: BMC Veterinary Research 2018 14:364

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  28. Content type: Research article

    The effects of the dietary oils with differing fatty acid profiles on rumen fermentation, microbial population, and digestibility in goats were investigated. In Experiment I, rumen microbial population and fer...

    Authors: I. Nur Atikah, A. R. Alimon, H. Yaakub, N. Abdullah, M. F. Jahromi, M. Ivan and A. A. Samsudin

    Citation: BMC Veterinary Research 2018 14:344

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  29. Content type: Research article

    Many reports describe the cutaneous signs of adverse food reactions (AFR) in the dog and cat. However, various non-cutaneous clinical signs are less well described. Our objective was to systematically evaluate...

    Authors: Ralf S. Mueller and Thierry Olivry

    Citation: BMC Veterinary Research 2018 14:341

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  30. Content type: Research article

    Lawsonia intracellularis is one of the world’s most important infectious diseases in pork production with regard to economic losses. So far, studies are missing that describe the effects of a natural infection of...

    Authors: Christian Visscher, Jasmin Mischok, Saara Sander, Marion Schmicke, Eva-Ursula Peitzmeier, Isabel von dem Busche, Karl Rohn and Josef Kamphues

    Citation: BMC Veterinary Research 2018 14:323

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  31. Content type: Research article

    Subacute ruminal acidosis (SARA) is characterized by a ruminal pH depression, and microbiota can also be affected by a higher acidity and/or dietary changes. Previous studies have revealed similar patterns in ...

    Authors: Yo-Han Kim, Rie Nagata, Akira Ohkubo, Natsuki Ohtani, Shiro Kushibiki, Toshihiro Ichijo and Shigeru Sato

    Citation: BMC Veterinary Research 2018 14:310

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  32. Content type: Research article

    In order to ensure sustainability of aquaculture production of carnivourous fish species such as the gilthead seabream (Sparus aurata, L.), the impact of the inclusion of alternative protein sources to fishmeal, ...

    Authors: Guillem Estruch, Maria Carmen Collado, Raquel Monge-Ortiz, Ana Tomás-Vidal, Miguel Jover-Cerdá, David S Peñaranda, Gaspar Pérez Martínez and Silvia Martínez-Llorens

    Citation: BMC Veterinary Research 2018 14:302

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  33. Content type: Research article

    Adverse food reactions (AFRs) are defined as abnormal responses to an ingested food or food additive. Diagnosis and treatment of AFRs consist of the complete elimination of these ingredients in the dietary tri...

    Authors: Elena Pagani, Maria de los Dolores Soto del Rio, Alessandra Dalmasso, Maria Teresa Bottero, Achille Schiavone and Liviana Prola

    Citation: BMC Veterinary Research 2018 14:283

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  34. Content type: Research article

    Selenium (Se) and vitamin E (Vit E) can act synergistically and affect biological processes, mainly antioxidant and immunity. The use of excess dietary Vit E and Se in animals’ feed could enhance immune respon...

    Authors: A. M. Dalia, T. C. Loh, A. Q. Sazili, M. F. Jahromi and A. A. Samsudin

    Citation: BMC Veterinary Research 2018 14:249

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  35. Content type: Research article

    Fatness is an unwanted side effect of genetic selection in broiler chickens. In this study, we introduce mountain celery powder as a feed supplement to suppress lipogenesis and improve antioxidant status in br...

    Authors: Behnam Ahmadipour, Hossein Hassanpour and Fariborz Khajali

    Citation: BMC Veterinary Research 2018 14:234

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  36. Content type: Research article

    Neonatal calf diarrhea is generally caused by infectious agents and is a very common disease in bovine practice, leading to substantial economic losses. Tannins are known for their astringent and anti-inflamma...

    Authors: F. Bonelli, L. Turini, G. Sarri, A. Serra, A. Buccioni and M. Mele

    Citation: BMC Veterinary Research 2018 14:227

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  37. Content type: Research article

    Protein concentration and quality in cat food can vary considerably, and the impact on feline urine composition and nutrient supply is of high practical relevance. In the present study, 6 canned diets with var...

    Authors: Nadine Paßlack, Barbara Kohn, Marcus G. Doherr and Jürgen Zentek

    Citation: BMC Veterinary Research 2018 14:225

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  38. Content type: Research article

    Chitosan was used as an alternative to promote the growth of weaned piglets. And low-molecular-weight chitosan (LC) is one of chitosan derivatives and maintain beneficial biological properties of chitoson. The...

    Authors: Shenglan Hu, Yu Wang, Xiaolu Wen, Li Wang, Zongyong Jiang and Chuntian Zheng

    Citation: BMC Veterinary Research 2018 14:215

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  39. Content type: Research article

    Although the European Pet Food Industry Federation (FEDIAF) stated that labels must be accurate and provide detailed information on the ingredients, mislabeling of pet food has been documented by several autho...

    Authors: Rebecca Ricci, Daniele Conficoni, Giada Morelli, Carmen Losasso, Leonardo Alberghini, Valerio Giaccone, Antonia Ricci and Igino Andrighetto

    Citation: BMC Veterinary Research 2018 14:209

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  40. Content type: Research article

    Diet supplementation with polyphenols is a novel strategy to improve meat quality in livestock, by preventing oxidative deterioration of lipids and protein. Polyphenols have beneficial effects on both human an...

    Authors: Roberta Cimmino, Carmela M. A. Barone, Salvatore Claps, Ettore Varricchio, Domenico Rufrano, Mariangela Caroprese, Marzia Albenzio, Pasquale De Palo, Giuseppe Campanile and Gianluca Neglia

    Citation: BMC Veterinary Research 2018 14:181

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  41. Content type: Research article

    Cyclooxygenase 2 (COX-2) is an inducible isoform by cellular activation, proinflammatory cytokines and growth factors. The aims of the current study were to evaluate COX-2 immunoexpression in epithelial and la...

    Authors: Jorge Castro-López, Antonio Ramis, Marta Planellas, Mariana Teles and Josep Pastor

    Citation: BMC Veterinary Research 2018 14:158

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  42. Content type: Research article

    Coccidiosis is a prevalent problem in chicken production. Dietary addition of coccidiostats and vaccination are two approaches used to suppress coccidia in the practical production. Methionine (Met) is usually...

    Authors: Anqiang Lai, Guozhong Dong, Daijun Song, Tan Yang and Xiaolong Zhang

    Citation: BMC Veterinary Research 2018 14:140

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  43. Content type: Research article

    Intestinal mucosal S100A12 and myeloperoxidase (MPO) are inflammatory biomarkers in humans with inflammatory bowel disease (IBD). However, these biomarkers have not been studied in the intestinal mucosa of dog...

    Authors: Mohsen Hanifeh, Satu Sankari, Minna M. Rajamäki, Pernilla Syrjä, Susanne Kilpinen, Jan S. Suchodolski, Romy M. Heilmann, Phillip Guadiano, Jonathan Lidbury, Jörg M. Steiner and Thomas Spillmann

    Citation: BMC Veterinary Research 2018 14:125

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  44. Content type: Research article

    Feeding dogs with diets rich in protein may favor putrefactive fermentations in the hindgut, negatively affecting the animal’s intestinal environment. Conversely, prebiotics may improve the activity of health-...

    Authors: Carlo Pinna, Carla Giuditta Vecchiato, Carmen Bolduan, Monica Grandi, Claudio Stefanelli, Wilhelm Windisch, Giuliano Zaghini and Giacomo Biagi

    Citation: BMC Veterinary Research 2018 14:106

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  45. Content type: Research article

    The natural incidence of left displacement of abomasum (LDA) in dairy cows was high. The diagnosis of LDA usually relies on characteristic physical exam findings but that transabdominal ultrasound is a useful ...

    Authors: Xin-Wei Li, Qiu-Shi Xu, Ren-He Zhang, Wei Yang, Yu Li, Yu-Ming Zhang, Yu Tian, Min Zhang, Zhe Wang, Guo-wen Liu, Cheng Xia and Xiao-Bing Li

    Citation: BMC Veterinary Research 2018 14:44

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  46. Content type: Research article

    Diagnosing IBD in horses is challenging and requires a multimodal approach, since no conclusive diagnostic test is available.

    Authors: Berit Boshuizen, Margreet Ploeg, Jeroen Dewulf, Sanne Klooster, Marco de Bruijn, Marie- Thérèse Picavet, Katrien Palmers, Lukas Plancke, Hilde De Cock, Mathijs Theelen and Catherine Delesalle

    Citation: BMC Veterinary Research 2018 14:21

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  47. Content type: Research article

    Acute ruminal lactic acidosis (ARLA) is a major nutritional and metabolic disorder usually characterized by excessive or non-adapted intake of diets rich in nonstructural carbohydrates. Feed additives that reg...

    Authors: Leonardo Frasson Reis, Rejane Santos Sousa, Francisco Leonardo Costa Oliveira, Frederico Augusto Mazzocca Lopes Rodrigues, Carolina Akiko Sato Cabral Araújo, Enoch Brandão Souza Meira-Júnior, Raimundo Alves Barrêto-Júnior, Clara Satsuki Mori, Antonio Humberto Hamad Minervino and Enrico Lippi Ortolani

    Citation: BMC Veterinary Research 2018 14:9

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