Fig. 3From: A six-month prospective, randomised, double-blinded, placebo-controlled, crossover, dietary trial design to investigate the potential of psychobiotics on seizure semiology and comorbidities in canine epilepsy: study protocolStudy design of a six-month prospective, randomised, double-blinded, placebo-controlled, crossover, dietary trial. The aim of the current study is to investigate the influence of Bifidobacterium longum on the behaviour profile and secondarily on seizure semiology of 34 dogs. In the first phase each dog receives the allocated supplement (probiotic vs. placebo) alongside its normal diet for 3 months. The second phase starts after a wash out period of 3 weeks, followed by administering the other supplement (crossover) for another 3 months. Halfway through each study phase interim check-ups are conductedBack to article page