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Table 2 Minimal inhibitory concentration (MIC) of LEAP2 against bacteria and fungus

From: Host defence peptide LEAP2 contributes to antimicrobial activity in a mustache toad (Leptobrachium liui)

Bacteria/fungus

Strains

Medium

Temperature (°C)

MIC (μM)

Ll-LEAP2

Sm-LEAP2 [23]

Aeromonas hydrophila

ATCC7966

LB

37

5.6

>  50

Escherichia coli

K12

LB

37

2.78

25–50

Listeria monocytogenes

ATCC19115

BHI

37

–

NT

Pichia pastoris (fungus)

GS115

YPD

30

–

NT

Proteus mirabilis

ATCC25933

LB

37

–

NT

Pseudomonas aeruginosa

ATCC27853

LB

37

22.2

25–50

Salmonella enterica

ATCC13076

LB

37

2.78

NT

Shigella sonnei

ATCC25931

LB

37

–

NT

Staphylococcus aureus

ATCC6538

LB

37

11.1

>  50

Vibrio alginolyticus

ATCC17749

TSB

28

–

>  50

Vibrio parahaemolyticus

ATCC33847

TSB

28

–

>  50

  1. –: no inhibition detected at 22.2 μM. NT not detected