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Table 5 Doppler-derived echocardiographic parameters in brachycephalic breeds with and without signs of BOAS

From: Echocardiographic parameters in French Bulldogs, Pugs and Boston Terriers with brachycephalic obstructive airways syndrome

Variable (unit)

FB with signs of BOAS (n = 20)

FB without signs of BOAS (n = 10)

Pugs with signs of BOAS (n = 10)

Pugs without signs of BOAS (n = 5)

BST with signs of BOAS (n = 9)

MVE (m/s)

0.79 (0.68–0.96)

0.80 (0.71–0.98)

0.66 (0.56–0.76)

0.67 (0.56–0.75)

0.74 (0.64–0.84)

MVA (m/s)

0.58 (0.51–0.81)

0.53 (0.45–0.62)

0.45 (0.42–0.52)

0.42 (0.36–0.49)

0.51 (0.44–0.57)

MVE/A

1.37 (1.17–1.80)

1.50 (1.41–1.76)

1.45 (1.20–1.80)

1.52 (0.93–1.61)

1.66 (1.14–1.81)

TVE (m/s)

0.78 (0.60–0.87)**

0.57 (0.43–0.68)**

0.63 (0.50–0.75)

0.49 (0.34–0.70)

0.73 (0.57–0.82)

TVA (m/s)

0.47 (0.39–0.61)

0.39 (0.34–0.46)

0.39 (0.29–0.47)

0.31 (0.23–0.47)

0.41 (0.37–0.47)

TVE/A

1.52 (1.46–1.69)

1.36 (1.21–1.49)

1.89 (1.49–1.96)

1.60 (1.34–1.69)

1.62 (1.44–1.85)

MVE/TVE

1.04 (0.95–1.27)**

1.60 (1.34–1.73)**

1.05 (0.95–1.28)

1.37 (0.85–2.15)

1.04 (0.83–1.34)

MVA/TVA

1.16 (1.01–1.37)

1.36 (1.07–1.61)

1.22 (0.90–1.48)

1.45 (0.83–2.00)

1.16 (0.90–1.35)

Sm (cm/s)

11.0 (6.80–12.60)

8.85 (7.53–12.38)

7.0 (5.63–9.30)

6.30 (5.35–8.15)

10.20 (8.15–10.90)

Em (cm/s)

10.30 (8.20–12.90)

12.20 (9.65–13.20)

7.75 (6.88–9.93)

6.10 (4.35–8.75)

9.50 (7.80–13.0)

MVE/Em (cm/s)

7.60 (6.10–9.90)

7.10 (6.55–7.75)

7.80 (7.10–9.03)**

11.0 (8.15–13.75)**

7.10 (5.95–9.0)

Am (cm/s)

6.0 (4.50–8.10)✩

6.95 (4.78–7.90)

4.10 (2.80–7.68)✩

6.0 (4.90–7.85)

8.20 (6.85–9.65)

Si (cm/s)

5.90 (4.60–9.50)✩

7.50 (5.33–9.75)

6.65 (5.20–7.55)✩

5.30 (4.35–6.05)

8.10 (6.15–8.45)✩

Ei (cm/s)

7.50 (5.0–8.80)

6.60 (5.78–7.68)

6.50 (4.58–8.13)

5.50 (4.55–6.10)

7.20 (5.0–8.10)

MVE/Ei (cm/s)

10.70 (9.50–12.70)

12.30 (10.10–15.85)

10.35 (8.0–14.08)

11.80 (9.75–16.05)

10.50 (8.90–16.10)

Ai (cm/s)

5.20 (4.0–7.30)

5.85 (4.98–7.58)

6.70 (4.90–7.48)**

4.40 (3.65–4.75)**

5.40 (4.80–7.80)

St (cm/s)

9.20 (7.60–13.90)

7.90 (6.73–10.10)

9.10 (6.65–11.95)

6.60 (6.05–9.0)

11.10 (7.85–11.45)

Et (cm/s)

10.20 (8.30–11.80)

8.85 (8.38–10.75)

9.25 (8.05–11.5)

7.60 (7.10–9.55)

10.30 (9.25–11.5)

TVE/Et (cm/s)

7.38 (5.83–8.27)

6.17 (4.38–7.24)

7.03 (5.60–8.09)

5.26 (4.23–8.91)

7.44 (5.93–8.52)

At (cm/s)

7.60 (7.10–11.90)

8.70 (6.33–10.78)

7.75 (5.70–8.50)**

5.10 (4.60–6.75)**

8.30 (6.55–9.95)

GSAplax (%)

19.30 (14.56–23.08)

18.70 (16.75–21.20)

18.80 (13.68–21.4)

15.80 (13.80–20.35)

20.35 (16.90–26.53)

GSLV4ch (%)

20.05 (16.68–21.05)

19.30 (14.50–21.90)

16.40 (12.75–20.9)

17.50 (13.95–19.60)

20.60 (17.33–22.03)

GSLV2ch (%)

21.20 (16.33–23.0)

19.10 (14.75–21.30)

17.90 (12.50–18.95)

13.70 (11.90–18.75)

21.50 (16.2–28.48)

GSLV (%)

19.60 (18.35–22.03)

18.83 (16.60–21.85)

18.82 (12.68–21.10)

15.67 (13.75–19.0)

21.90 (17.25–24.2)

GSRV (%)

21.05 (16.10–24.08)

17.15 (14.28–19.73)

18.1 (14.80–22.93)

14.40 (12.20–16.15)

21.80 (19.4–25.29)

  1. Data are presented as medians (interquartile range: 25th – 75th percentile), Ai Late diastolic interventricular annular velocity, Am Late diastolic mitral annular velocity, At Late diastolic tricuspid annular velocity, BOAS Brachycephalic obstructive airway syndrome, BST Boston Terriers, Ei Early diastolic interventricular annular velocity, Em Early diastolic mitral annular velocity, Et Early diastolic tricuspid annular velocity, FB French Bulldogs, GSAplax Left ventricular global strain in apical long axis 5 chamber view, GSLV Mean left ventricular global strain, GSLV4ch Left ventricular global strain in apical long axis 4 chamber view, GSLV2ch Left ventricular global strain in apical long axis 2 chamber view, GSRV Right ventricular global strain in apical long axis view, MVA Late diastolic mitral wave, MVE Early diastolic mitral wave, MVE/A early diastolic mitral wave to late diastolic mitral wave ratio, Si Peak systolic interventricular annular velocity, Sm Peak systolic mitral annular velocity, St Peak systolic tricuspid annular velocity, TVA Late diastolic tricuspid wave, TVE Early diastolic tricuspid wave
  2. ✩ = significant differences between brachycephalic dogs with signs of BOAS and non-brachycephalic dogs (data presented in Tables 2 and 3), ** = significant differences between brachycephalic dog with and without signs of BOAS