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Fig. 5 | BMC Veterinary Research

Fig. 5

From: Matrine combined with Osthole inhibited the PERK apoptosis of splenic lymphocytes in PCV2-infected mice model

Fig. 5

Effect of Matrine combined with Osthole on pathological change of lung and spleen induced by PCV2 infection. Representative tissue histology images of mice at 11 d (6 d after compounds adminstration) after PCV2 infection were showed. Sale bar = 50 μm. a Results of lungs HE staining demonstrated that compared with normal control, PCV2 group displayed severe thickened alveoli septum and alveolar space decreased. b The rusults of spleen HE staining showed that loss of lymphocytes and infiltration of macrophages and eosinophils in the PCV2 group While the pathological changes of each treatment group were significantly alleviated, especially in the group with Matrine combined with Osthole was the best

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