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Table 3 Mean PRRSv PCR treshold cycle (Ct) values for different samples collected from farrowed piglets in the PRRSV challenge study in pregnant sows. Samples were collected on different days post challenge and days post-farrow. Values equal or higher than 37 were considered as not detected (nd) and are not included in the calculation of the mean Ct values. Values between brackets indicate the ratio of positive samples by total number of samples

From: Effects of a water-soluble formulation of tylvalosin on disease caused by porcine reproductive and respiratory syndrome virus alone in sows or in combination with Mycoplasma hyopneumoniae in piglets

  

Mean Ct values of positive samples

(number of positive samples/ number of samples)

  

Days post-farrow

  

0

2

9

16

21–25

Faecal swab

Untreated-unchallenged

nd

(0/95)

nd

(0/70)

nd

(0/64)

nd

(0/63)

nd

(0/61)

Untreated-challenged

33.3

(14/41)

30.9

(29/29)

30.6

(10/10)

35.5

(7/8)

33.9

(3/8)

Treated-challengeda

34.0

(19/36)

31.5

(26/28)

30.4

(12/13)

32.8

(5/5)

nd

(0/9)

Oral swab

Untreated-unchallenged

nd

(0/95)

nd

(0/70)

nd

(0/64)

nd

(0/63)

nd

(0/60)

Untreated-challenged

35.2

(12/41)

32.5

(21/29)

34.9

(6/10)

33.2

(4/8)

34.5

(3/8)

Treated-challengeda

34.2.

(23/36)

34.4

(18/28)

33.1

(10/13)

34.6

(7/10)

35.8

(2/10)

Blood serum

Untreated-unchallenged

nd

(0/93)

nd

(0/69)

nd

(0/64)

nd

(0/62)

nd

(0/60)

Untreated-challenged

22.3

(36/41)

16.0

(28/28)

17.1

(10/10)

19.2

(7/7)

23.8

(8/8)

Treated-challengeda

19.7.

(34/35)

16.7

(28/28)

16.0

(13/13)

18.1

(10/11)

24.0

(9/9)

  1. ns no sample
  2. nd not detected (Ct ≥ 37)
  3. aSows treated with tylvalosin at 5 mg/kg per day in drinking water from 3 days before challenge until farrowing