Table 1 Biomarkers measured in the fluid recovered from the reproductive tract of sows in the PRRSV challenge study in pregnant sows. Samples were collected after euthanasia approximately 21 days post farrow. Treatement description is in Table 5

CCL3L1

252.46 ± 282.01

214.86 ± 189.28

687.57 ± 601.19

0.807

0.215

0.252

GM-CSF

405.76 ± 231.15

1636.01 ± 1865.2

496.69 ± 373.04

0.168

0.200

0.688

IFNa

65,035.47 ± 29,915.14

57,990.61 ± 20,895.11

48,621.73 ± 16,753.99

0.670

0.457

0.336

IFNg

2848.39 ± 3172.53

1404 ± 1616.26

858.35(296.91, 5390.5)

0.393

1.000

0.607

IL-10

275.33 ± 177.47

543.01 ± 501.47

256.43 ± 83.5

0.266

0.224

0.840

IL-12p40p70

16,785.44 ± 7702.19

46,381.72 ± 45,447.95

24,129.79 ± 13,604.8

0.174

0.302

0.384

IL-13

3073.07 ± 2044.33

2813.8 ± 1435.92

2128.84 ± 301.75

0.818

0.304

0.363

IL-17A

71.54 ± 56.64

62.18 ± 38.44

126.28 ± 127.6

0.763

0.394

0.470

IL-18

3,407,125.07 ± 2,641,856.22

2,343,833.69 ± 831,018.25

2,547,434.94 ± 675,746.05

0.429

0.683

0.518

IL-1a

84,130.91 ± 66,856.55

54,783.06 ± 29,747.06

70,931.41 ± 44,128.24

0.403

0.551

0.733

IL-1b

1318.08 ± 1140.23

1199.56 ± 512.52

1146.54 ± 380.62

0.838

0.856

0.765

IL-1ra

3694.59 ± 4147.84

6244.39 ± 8219.92

1845.21 ± 1088.76

0.526

0.250

0.386

IL-4

3701.24 ± 3038.7

4479.77 ± 1604.22

5782 ± 4597.23

0.625

0.619

0.471

IL-6

1448.03 ± 1142.23

1558.83 ± 627.73

1744.6 ± 928

0.853

0.741

0.680

IL-8

17.31 ± 10.37

41.92 ± 38.88

10.29 ± 7.55

0.189

0.105

0.279

MIG

3821.29 ± 2765.76

2720.92 ± 954.38

3077.41 ± 1720.89

0.436

0.724

0.637

MIP-1b

13.84 ± 10.81

12.51 ± 11.71

69.37 ± 85.48

0.849

0.276

0.285

PECAM-1

3926.3 ± 2141.81

4269.73 ± 2656.54

2853.67 ± 814.45

0.818

0.265

0.347

TGFb1

221,572.86 ± 114,642.43

244,924.97 ± 72,559.89

256,329.02 ± 92,330.07

0.706

0.843

0.630

TNFa

26,530.25 ± 12,185.13

82,296.32 ± 61,218.41

35,245.93 ± 17,273.66

0.076

0.125

0.431