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Table 4 The important parameters in the AUC24/MIC using the inhibitory form Emax sigmoid model after intramammary administration

From: A PK/PD model for the evaluation of clinical rifaximin dosage for the treatment of dairy cow mastitis induced by Escherichia coli

Parameters

AUC24/MIC

For2 log10 CFU/gland reduction

57.80

For2.5 log10 CFU/gland reduction

73.63

Log Emax (log10 CFU/gland)

2.36 ± 0.50

Log Emax-log E0 (log10 CFU/gland)

6.91 ± 0.63

EC50 (h)

38.85 ± 4.43

Slope (N)

1.35 ± 0.18

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BMC Veterinary Research

ISSN: 1746-6148

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