Table 1 Identification of candidate protein spots in healthy dogs’ tears using LC-MS/MS analysis
From: Analysis and comparison of tear protein profiles in dogs using different tear collection methods
Spot ID | Identified proteins | Mass | pI | Protein score | Biological function |
|---|---|---|---|---|---|
1 | Actin, cytoplasmic 1 | 44,793 | 5.06 | 405 | Retina homeostasis |
2 | Albumin | 53,040 | 5.87 | 41 | Antimicrobial |
3 | Albumin | 53,040 | 5.87 | 40 | Antimicrobial |
4 | Aldehyde dehydrogenase, dimeric NADP-preferring | 51,193 | 6.44 | 58 | Preventing corneal damage caused by ultraviolet light. |
5 | Alpha fetoprotein | 73,962 | 5.95 | 1241 | Heavy metal binding |
6 | Haptoglobin | 36,890 | 5.72 | 208 | Acute inflammatory response |
7 | Haptoglobin | 36,890 | 5.72 | 124 | Acute inflammatory response |
8 | Haptoglobin | 36,890 | 5.72 | 61 | Acute inflammatory response |
9 | Induced myeloid leukemia cell differentiation protein Mcl-1 homolog | 36,884 | 5.49 | 22 | Regulation of apoptotic process |
10 | Keratin 75 | 60,536 | 8.06 | 45 | Establishment of skin barrier |
11 | Lactoferrin | 70,444 | 8.00 | 47 | Antimicrobial |
12 | Lipocalin 1 | 21,872 | 5.67 | 371 | Antimicrobial |
13 | NCCRP1, F-box associated domain containing | 38,977 | 5.97 | 31 | Regulation of cell population proliferation |
14 | Stratifin | 27,930 | 4.70 | 503 | Establishment of skin barrier |