A new S. suis serotype 3 infection model in pigs: lack of effect of buprenorphine treatment to reduce distress

BMC Veterinary Research

Table 2 Reisolation of the S. suis cps3 challenge strain from piglets after intravenous application of 2 × 10⁸ CFU

buprenorphine	Number of piglets positive for the isolation of the challenge strain in an inner organ^b, serosa or joint fluid	Number of piglets positive for the isolation of the challenge strain in ≥ 2 organs^b	Number of piglets in which the S. suis challenge strain^a was isolated from
buprenorphine			Tonsils^h	Lung^c	Serosa^d	Spleen	Liver	Brain, CSF^e	Joint fluid^f	Endocard
untreated	3^g/8	3^g/8	2/8	1/8	0/8	2/8	1/8	1/8	2/8	1/8
treated	2^g/8	2^g/8	3/8	2/8	2/8	2/8	2/8	2/8	1/8	2/8

^aThe challenge strain was identified by MP- PCR combined with a serotype specific monoplex PCR
^bInner organ refers to lung, spleen, liver, brain, CSF or endocard but not the tonsils
^cOne cranial lobe was investigated
^dPleural, peritoneal or pericardial cavity
^eCerebrospinal fluid
^fPunctures of both tarsal and carpal joints were investigated in each animal. In case of lameness additional joint punctures of the respective limb were screened
^gReisolation of the challenge strain only in prematurely euthanized piglets
^hReisolation of challenge strain from tonsils in one prematurely euthanized and four surviving piglets

ISSN: 1746-6148