Table 2 Intraoperative rescue fentanyl bolus administration and postoperative analgesia during the first 24 hours after surgery of 132 dogs undergoing thoracolumbar (cranial to the 1st lumbar vertebra) or lumbar (caudal to the 1st lumbar vertebra) and in which a bilateral erector spinae block (group ESPB) or a fentanyl infusion (group CRI) was used. Fentanyl administration and dosage, time from start of surgery to first rescue fentanyl bolus administration and methadone dosage are reported as median (range). Odd ratio (OR) and 95% Confidence intervals (CI) is reported when appropriate. * indicates reciprocal OR
Group | ESPB (n = 93) | CRI (n = 39) | ESPB vs CRI p value | OR (95% CI) | ||
|---|---|---|---|---|---|---|
Information | ||||||
Rescue fentanyl bolus administration (n. of dogs) | 51 (54.8%) | 22 (56.4%) | > 0.99 |  | ||
Rescue fentanyl bolus administration during thoracolumbar surgery (n. of dogs) | 37 (39.8%) | 7 (18%) | 0.13 | 2.40 (0.85–6.93) | ||
Rescue fentanyl bolus administration during lumbar surgery (n. of dogs) | 14 (15%) | 14 (36%) | 0.037 | 4.25 (1.08–13.56) * | ||
Number of rescue fentanyl boluses administered | 1 (1–4) | 2 (1–7) | 0.006 |  | ||
Total rescue fentanyl dose (μg/kg/hour) | 1.7 (0.4–6) | 1.6 (0.75–5.1) | 0.59 |  | ||
Time from start of surgery to first rescue fentanyl bolus administration (min) | 25 (5–105) | 10 (5–50) | < 0.0001 |  | ||
Postoperative oral analgesia (n. of dogs) | Gabapentin, NSAID | 71 (76.3%) | 39 (100%) | 0.0008 | Â | |
Gabapentin, NSAID, amantadine | 1 (1.1%) | 0 (0%) | 1 | |||
Gabapentin, NSAID, paracetamol | 1 (1.1%) | 0 (0%) | 1 | |||
Gabapentin | 13 (13.9%) | 0 (0%) | 0.01 | |||
Gabapentin, paracetamol | 2 (2.2%) | 0 (0%) | 1 | |||
Gabapentin, steroid | 2 (2.2%) | 0 (0%) | 1 | |||
Gabapentin, steroid, paracetamol | 3 (3.2%) | 0 (0%) | 0.55 | |||
Postoperative methadone requirement | First 6 hours | At least one dose administrated (n.) | 15 / 86 (17.4%) | 17 (43.6%) | 0.003 | 3.66 (1.60–8.71) * |
Dose (mg/kg) | 0.2 (0.2–0.5) | 0.2 (0.2–0.4) | 0.18 |  | ||
6–12 hours | At least one dose administrated (n. of dogs) | 9 / 86 (10.5%) | 15 (38.5%) | 0.0005 | 5.35 (2.14–12.98) * | |
Dose (mg/kg) | 0.2 (0.2–0.4) | 0.2 (0.2–0.4) | 0.24 |  | ||
12–24 hours | At least one dose administrated (n. of dogs) | 6/86 (7%) | 6 (15.4%) | 0.19 |  | |
Dose (mg/kg) | 0.3 (0.2–0.4) | 0.2 (0.2–0.4) | > 0.99 |  | ||