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Fig. 2 | BMC Veterinary Research

Fig. 2

From: Tissue S100/calgranulin expression and blood neutrophil-to-lymphocyte ratio (NLR) in dogs with lower urinary tract urothelial carcinoma

Fig. 2

S100/calgranulin-positive cell counts in tissue biopsies of dogs with lower urinary tract diseases. A S100A8/A9+ cell counts per mm2 were numerically (but not statistically) higher in dogs with non-neoplastic (inflammatory) urinary tract diseases (NNUTD; median: 312, range: 0–890) than in dogs with urothelial carcinoma (UC; median: 22, range: 0–98; P = 0.2382) and healthy controls (control; median: 21, range: 2–39; P = 0.2478). B S100A12+ cell counts per mm2 were significantly higher in dogs with UC (median: 15, range: 0–69) and dogs with NNUTD (median: 75, range: 0–540) than in healthy controls (median: 0, range: 0–7; P = 0.0267 and P = 0.0049, respectively), but no significant difference between UC and NNUTD (P = 0.1372). C The S100A8/A9+-to-S100A12.+ ratio (Cal-ratio) was significantly lower in dogs with UC (median: 2.0, range: 1.3–4.3) and dogs with NNUTD (median: 1.3, range: 0.8–6.7) than in healthy controls (median: 12.6, range: 1.8–13.2; P = 0.0062 and P = 0.0030, respectively), but did not significantly differ between UC and NNUTD (P = 0.2884)

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