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Table 3 Minimum inhibitory concentration (MIC) of antibiotics against microorganisms

From: Antibiotic-resistant status and pathogenic clonal complex of canine Streptococcus canis-associated deep pyoderma

Antibiotics

CLSI Break pointa

MIC (μg/ml)

S

I

R

P02

P03

P05

P23

O14

Penicillins

 Penicillin G

≤0.12

≥0.25

≤0.06

0.12

≤0.06

0.25

0.25

 Ampicillin

≤0.25

≥0.5

≤0.25

2

≤0.25

0.5

0.5

Penicillins/ β-lactamase inhibitors

 Amoxicillin/clavulanate

≤2/1

4/2

≥8/4

≤0.25/0.12

1/0.5

≤0.25/0.12

≤0.25/0.12

≤0.25/0.12

Cephems

 Cefaclor

≤1

2

≥4

≤2

4

≤2

16

8

 Cefazolin sodium

≤2

4

≥8

≤0.5

1

≤0.5

1

2

Anti-MRSA drugs

 Linezolid

≤2

≥4

2

4

2

2

2

 Vancomycin

≤1

≥2

≤0.5

8

≤0.5

1

≤0.5

  1. aAmpicillin and cefazolin sodium used Vet-08 criteria, while M-100 criteria were used for the remaining antibiotics. S, sensitive; I, Intermediate; R, Resistant. CLSI, Clinical & Laboratory Standards Institute