Fig. 4From: Silver-Silica nanoparticles induced dose-dependent modulation of histopathological, immunohistochemical, ultrastructural, proinflammatory, and immune status of broiler chickensRepresentative photomicrographs for ultrastructure morphology of muscle tissues from broiler chickens treated with different levels of Silica- silver nanoparticles (SiO2@AgNPs) for 35Â days: (A) Chickens treated with 8Â mg of SiO2@AgNPs showed irregular nucleus and abnormal nuclear envelope (arrow), with disrupted filament and Z band. B Chicken supplemented with 16Â mg of SiO2@AgNPs showed disintegrated nuclear chromatin, mild cytoplasmic vacuolization, irregular mitochondria (white arrows), and aggregations of SiO2@AgNPs deposits within the nuclear chromatin nearby the nuclear envelope (yellow arrows). C Chicken supplemented with 20Â mg of SiO2@AgNPs showed aggregations of SiO2@AgNPs deposits within the internal membrane of mitochondrial cristae (white arrow)Back to article page