Table 2 Cardiovascular and echocardiographic variables pre- and post- weight reduction for the dogs that achieved target weight reduction

ECG heart rate

115

(95- 140)

110

(88.75–137.5)

0.722

0.117

Heart rate variability (VVTI)

8.337

(6.7- 10.1)

8.856

(7.69–10.13)

0.367

0.272

SBP (mmHg)

178

(140–184)

148

(136.3–188.8)

0.554

0.164

Hs-cTnI (ng/mL)

0.013

(0.007–0.52)

0.012

(0.009–0.018)

0.657

0.147

NT-proBNP (pmol/L)

371.5

(257.8–530.0)

482.0

(345.0–558.0)

0.262

0.353

LA/Ao

1.305

(1.14–1.44)

1.295

(1.13–1.37)

0.894

0.013

LA major (cm)

3.4

(2.78–3.97)

3.335

(2.87–3.94)

0.722

0.125

LAmax/Ao

2.3

(2.06–2.42)

2.1

(1.75–2.29)

0.176

0.436

IVSd (mm)

10.25

(8.93–12.25)

9.65

(7.88–10.7)

0.158

0.419

LVIDd (mm)

35.2

(27.43–42.25)

34.45

(27.27–42.18)

0.556

0.363

LVFWd (mm)

9.3

(8.28- 10.88)

8.8

(7.9–9.48)

0.099

0.340

IVSs (mm)

13.4

(11.85–15.9)

11.75

(9.65–14.1)

0.029

0.643

LVIDs (mm)

23.75

(17.23–31.27)

25.45

(18.97–27.93)

0.272

0.323

LVFWs (mm)

13.3

(12.1–15.5)

10.55

(10.15–14.3)

0.017

0.702

IVSdN

Actual weight

0.41

(0.38–0.47)

0.41

(0.38–0.48)

0.610

0.158

Target weight

0.46

(0.41–0.55)

0.41

(0.38–0.49)

0.126

0.453

LVIDdN

Actual weight

1.31

(1.18–1.41)

1.41

(1.23–1.53)

0.092

0.498

Target weight

1.44

(1.32–1.60)

1.42

(1.26–1.54)

0.290

0.317

LVFWdN

Actual weight

0.44

(0.39–0.51)

0.42

(0.37–0.50)

0.610

0.158

Target weight

0.49

(0.43–0.55)

0.42

(0.37–0.51)

0.196

0.385

IVSsN

Actual weight

0.58

(0.49–0.68)

0.55

(0.48–0.59)

0.224

0.362

Target weight

0.63

(0.55–0.74)

0.56

(0.50–0.60)

0.011

0.744

LVIDsN

Actual weight

0.82

(0.72–0.93)

0.94

(0.81–1.04)

0.011

0.747

Target weight

0.91

(0.81–1.04)

0.95

(0.83–1.05)

0.196

0.385

LVFWsN

Actual weight

0.66

(0.54–0.71)

0.59

(0.54–0.64)

0.196

0.385

Target weight

0.72

(0.58–0.79)

0.60

(0.54–0.65)

0.009

0.770

EDV (mL)

32

(18–65)

33

(18–64)

0.507

0.200

EDVI (mL/kg)

Actual weight

1.67

(1.21–2.09)

2.02

(1.88–2.72)

0.008

0.770

Target weight

2.31

(1.80–2.59)

2.01

(1.88–2.72)

0.657

0.128

ESV (mL)

13

(6–38)

13

(7–35)

0.180

0.404

ESVI (mL/kg)

Actual weight

0.64

(0.42–1.13)

0.92

(0.67–1.41)

0.015

0.702

Target weight

0.90

(0.65–1.43)

0.92

(0.67–1.41)

0.158

0.407

E velocity (m/s)

0.67

(0.56–0.76)

0.71

(0.53–0.79)

0.965

0.026

MV E/A

1.175

(0.9–1.40)

1.03

(0.88–1.24)

0.824

0.119

E deceleration (ms)

90

(77.75–108)

86.5

(81.75–106.5)

0.76

0.103

IVRT (ms)

73.5

(62.5–87.75)

75

(69–94.25)

0.724

0.113

TAPSE (cm)

1.14

(0.9–1.5)

1.11

(0.8–1.36)

0.789

0.309

Septal E’/A’

0.695

(0.57–0.83)

0.7

(0.59–0.84)

0.45

0.242

Lateral E’/A’

0.715

(0.59–0.80)

0.7

(0.6–0.8)

0.824

0.081

Right E’/A’

0.65

(0.6–0.86)

0.67

(0.56–0.72)

0.262

0.371

Fractional shortening (%)

32

(27–39)

30

(26–34)

0.168

0.411

Ejection Fraction (%)

61

(53–65)

56

(41–69)

0.266

0.349