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Table 2 Performance of the three test (mZN, IC, ELISA) used to detect Cryptosporidium in feces of cattle compared with the CRS

From: Performance of diagnostic assays used to detect Cryptosporidium oocysts in faecal samples of cattle in Kuwait and genotyping of Cryptosporidium species

 

mZN

IC

ELISA

True positive

51

60

48

False positive

5

32

13

True negative

332

287

287

False negative

12

21

52

Sensitivity

(95% CI)

47.22%

(37.54% to 57.06%)

74.07%

(63.14% to 83.18%)

48.00%

(37.90% to 58.22%)

Specificity

(95% CI)

98.29%

(96.05% to 99.44%)

89.97%

(86.13% to 93.04%)

95.67%

(92.70% to 97.67%)

PPV

(95% CI)

91.07%

(80.70% to 96.14%)

65.22%

(56.85% to 72.74%)

78.69%

(67.63% to 86.71%)

NPV

(95% CI)

83.43%

(80.81% to 85.76%)

93.18%

(90.42% to 95.19%)

84.66%

(82.03% to 86.97%)

Accuracy

(95% CI)

84.50%

80.57% to 87.91%)

86.75%

(83.03% to 89.91%)

83.75%

(79.76% to 87.23%)

Cohen’s Kappa Test*

0.54

0.61

0.50

Moderate agreement

Substantial agreement

Moderate agreement

  1. * The interpretation of κ-values: no agreement (κ =  < 0), slight (κ = 0.00–0.20), fair (κ = 0.21–0.40), moderate (κ = 0.41–0.60), substantial (κ = 0.61–0.80), and perfect (κ = 0.81–1.00)