Table 2 List of the selected helper T-lymphocyte (HTL) epitopes and their interacting BoLA MHC-II alleles with binding information
SN | Peptide MHC II | Position | Antigenicity | Binding alleles | Prediction score | % Rank |
|---|---|---|---|---|---|---|
1 | SEAMSIDMNVLAKIN | 65–79 | 0.9694 | BoLA-DRB3*0401 | 0.700 | 0.70 |
BoLA-DRB3*0501 | 0.671 | 0.50 | ||||
BoLA-DRB3*0503 | 0.634 | 0.90 | ||||
BoLA-DRB3*0801 | 0.669 | 0.60 | ||||
BoLA-DRB3*1501 | 0.657 | 0.30 | ||||
BoLA-DRB3*1703 | 0.482 | 0.40 | ||||
BoLA-DRB3*1801 | 0.601 | 0.80 | ||||
BoLA-DRB3*1802 | 0.611 | 0.30 | ||||
BoLA-DRB3*1902 | 0.671 | 0.90 | ||||
BoLA-DRB3*2301 | 0.641 | 0.40 | ||||
BoLA-DRB3*2901 | 0.510 | 0.60 | ||||
BoLA-DRB3*3001 | 0.683 | 0.50 | ||||
BoLA-DRB3*3002 | 0.748 | 0.50 | ||||
BoLA-DRB3*3201 | 0.408 | 0.30 | ||||
BoLA-DRB3*3202 | 0.524 | 0.40 | ||||
BoLA-DRB3*3203 | 0.547 | 0.40 | ||||
BoLA-DRB3*3601 | 0.649 | 0.80 | ||||
2 | PVRTVAAPRVASVKV | 239–253 | 0.8232 | BoLA-DRB3*0101 | 0.805 | 2.00 |
BoLA-DRB3*1103 | 0.705 | 4.00 | ||||
BoLA-DRB3*2005 | 0.624 | 8.00 | ||||
BoLA-DRB3*3501 | 0.618 | 2.00 | ||||
3 | MKTYSSAPALKSKEV | 159–173 | 0.6597 | BoLA-DRB3*0101 | 0.761 | 4.00 |
BoLA-DRB3*0301 | 0.815 | 0.30 | ||||
BoLA-DRB3*0502 | 0.617 | 0.40 | ||||
BoLA-DRB3*0901 | 0.742 | 0.60 | ||||
BoLA-DRB3*0902 | 0.653 | 0.50 | ||||
BoLA-DRB3*1602 | 0.694 | 0.15 | ||||
BoLA-DRB3*2401 | 0.464 | 0.50 | ||||
BoLA-DRB3*2702 | 0.635 | 0.15 | ||||
BoLA-DRB3*2703 | 0.635 | 0.15 | ||||
BoLA-DRB3*2704 | 0.588 | 0.40 | ||||
BoLA-DRB3*2707 | 0.609 | 2.00 | ||||
BoLA-DRB3*2710 | 0.635 | 0.15 | ||||
BoLA-DRB3*4501 | 0.606 | 0.40 | ||||
BoLA-DRB3*46,011 | 0.505 | 0.80 | ||||
BoLA-DRB3*6201 | 0.696 | 5.00 | ||||
4 | STQNMAANNISYVIW | 379–393 | 0.5100 | BoLA-DRB3*0501 | 0.596 | 2.00 |
BoLA-DRB3*1501 | 0.602 | 0.70 | ||||
BoLA-DRB3*1903 | 0.611 | 4.00 | ||||
BoLA-DRB3*2301 | 0.557 | 1.50 | ||||
BoLA-DRB3*3001 | 0.677 | 0.50 | ||||
BoLA-DRB3*3002 | 0.670 | 1.50 |