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Fig. 2 | BMC Veterinary Research

Fig. 2

From: A novel strategy for developing vaccine candidate against Jaagsiekte sheep retrovirus from the envelope and gag proteins: an in-silico approach

Fig. 2

multi-epitope vaccine design. MHC1 epitopes for the envelope protein (blue colour), MHC1 epitopes for the gag protein (red colour), B cell epitopes for the envelope protein (purple colour), and B cells epitopes for the gag protein (orange colour). For both the envelope and the gag proteins, MHC-1 epitopes were linked to the GPGPG linker, while the B cells epitopes for both proteins were linked by the dipeptide KK linkers. As an adjuvant, Humanβ-defensin-3 (green colour) was added to the N terminals and is linked by the short EAAAK linker (black colour). At C-terminal, the his-tag (6 H) was added (brown colour)

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