Fig. 6

Histopathological examination of experimental birds infected with fowl adenovirus: A liver at 3 days post infection showing vacuolar degeneration of hepatocytes (arrow) (bar = 20), B liver at 3dpi showing focal infiltration of inflammatory cells (bar = 20), C bursa at 3dpi has no changes (bar = 100), D lung at 3dpi showing congestion of blood vessels (star) (bar = 100), E, F liver at 5dpi showing infiltration of inflammatory cells (star) (bar = 20), appearance of intranuclear basophilic inclusion bodies in hepatocytes (arrow) (bar = 10), G bursa at 5dpi showing severe lymph cytolysis (notched arrow) (bar = 20), H lung at 5dpi showing catarrhal exudates in the bronchi (star) (bar = 100), I liver at 7dpi showing inflammatory cells infiltration (star), vacuolar degeneration of hepatocytes (arrow) (100). J and K Bursa at 7dpi showing necrosis of medullary lymphocytes (arrow) (bar = 20). L Lung at 7dpi showing perivascular hemorrhage (notched arrow), vascular congestion (star) (bar = 100). M Liver at 9dpi showing severe infiltration of inflammatory cells (star) (bar = 20). N Bursa at 9dpi showing epithelial cysts (notched arrow) (bar = 20). O, P Lung at 9dpi showing hemorrhagic exudate in the parabronchi lumen (star), thrombosis in some blood vessels (notched arrow) (bar = 100). Q Liver at 35dpi showing severe lytic necrosis of all hepatic tissue (arrow) focal infiltration of inflammatory cells (notched arrow) (bar = 20). R,S Bursa at 35 days post infection showing severe medullary exhaustion of lymphocytes in lymphoid follicles (star), Hyperplasia of the bursal epithelium (notched arrow), epithelial cyst formation (arrow) (bar = 20). Lung at 35dpi showing peribronchial lymphoid hyperplasia (star) (bar = 20), (H&E)