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Table 2 PACK-CXL protocol details

From: The bactericidal effect of two photoactivated chromophore for keratitis-corneal crosslinking protocols (standard vs. accelerated) on bacterial isolates associated with infectious keratitis in companion animals

PACK-CXL

Standard

Accelerated

Treatment target

Bacterial suspension

Soak time and interval

30 min, continuous: bacteria suspended in Ri/NaCl solution

Chromophore

Riboflavin (Vitamin B2 Streuli, Uznach, Switzerland)

Chromophore carrier

0.9% NaCl (B. Braun Medical AG, Sempach, Switzerland)

Chromophore osmolarity

Iso-osmolar

Chromophore concentration

0.1%

Light source

UV-Xtm illumination system (version 1000), IROC, Switzerland

CCL-VARIO Cross-linking system, Peschke Trade, Switzerland

Wavelength (nm)

365

Irradiation mode

Continuous

Fluence (J/cm2)

5.4

Intensity (mW/cm2)

3

18

Treatment time (minutes)

30

5

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BMC Veterinary Research

ISSN: 1746-6148

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