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Fig. 7 | BMC Veterinary Research

Fig. 7

From: The combination of high glucose and LPS induces autophagy in bovine kidney epithelial cells via the Notch3/mTOR signaling pathway

Fig. 7

Schematic diagram for the proposed autophagy signaling pathways in MDBK cells regulated by the combination effect of HG and LPS. In HG and LPS-stimulated MDBK cells, the Notch3-mediated mTOR signaling pathway is activated, resulting in the activation of autophagy-related proteins and genes. Abbreviations HG: High glucose; LPS: Lipopolysaccharide; MDBK: Madin-darby bovine kidney; mTOR: Mammalian target of rapamycin; DMEM: Dulbecco’s Modified Eagle Medium; CCK-8: Cell counting kit-8; qRT-PCR: Quantitative real-time PCR; TEM: Transmission electron microscopy

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BMC Veterinary Research

ISSN: 1746-6148

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