Fig. 3

Subpleural ground-glass opacities with distinct margin were observed in the dorsal regions of the bilateral caudal lung lobes (black arrowhead) on lung high-resolution computed tomography (HRCT) (A). At necropsy, the dorsally distributed lesions on lung HRCT corresponded to the multifocal to coalescent dark-red foci (white arrow) on bilateral caudal lobes (B). Histopathology identified the fibrotic narrowing of the bronchioles (C) (Bar scale = 50 μm), and the alveolar septa around these bronchioles was thickened by moderate amount of fibrous connective tissue illustrated using Masson’s Trichrome staining (D) (Bar scale = 500 μm)