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Table 5 The result of migration inhibition of 5-hydroxy-9,10-dioxo-9,10-dihydroanthracene-1-sulfonamide (LLL12) on the primary cells derived from feline injection site sarcoma (FISS) following incubation with different concentrations for 24 hours evaluated by cell migration assaya

From: Investigating the role of signal transducer and activator of transcription 3 in feline injection site sarcoma

LLL12 (μM) FISS-10   
Average % of control SD
2 409.831 42.1* 2.611
1 721.171 80.9 75.594
0.5 682.277 80.5 31.343
0.25 849.18 97.2 83.353
0.125 753.586 81.4 19.806
0 871.470 97.2 40.710
DMSO 942.025 100 5.815
  1. *Statistically significant from the DMSO control (P < 0.05)
  2. a The migration of FISS cells was determined by the distance (μm) of cells that cross into the wound area from their reference point at time zero. The measurement included at least 50 readings of distance for each sample and each experiment was done in triplicate