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Fig. 7 | BMC Veterinary Research

Fig. 7

From: Enhancement of critical-sized bone defect regeneration using UiO-66 nanomaterial in rabbit femurs

Fig. 7

Histological assessment of critical-sized bone defect repair in rabbit femurs. (A) and (B) femoral condyle sections stained with Hematoxylin and Eosin from the control and UiO-66 implanted groups at weeks 4, 8, and 12 after surgery. (C) PAS & Hematoxylin- stained bone defect sites in control (a-c) and UiO-66 implanted (d-f) groups at different evaluation times. MSC: mesenchymal stem cell; Ob: osteoblast; Oc: osteocyte; Ocl: osteoclast; Og: osteogenic cells; Os: osteoid tissue; BM: bone matrix; SB: spongy bone; WB: woven bone; LB: lamellar bone; M: macrophage; L: lymphocyte; black asterisks: implanted UiO-66 nanomaterial; red arrows: newly formed bone. The scale bars in (A) = 1 mm, (B a-c,g-i) = 100 μm, and in (B d-f, j-l) and (C) = 50 μm

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