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Fig. 2 | BMC Veterinary Research

Fig. 2

From: Molecular epidemiological study of germline APC variant associated with hereditary gastrointestinal polyposis in dogs: current frequency in Jack Russell Terriers in Japan and breed distribution

Fig. 2

Blood relationships of Jack Russell Terriers with germline APC variant. Family tree constructed according to pedigree certificates of APC variant carriers. A Family tree containing paternal half-sisters, JRT203 and JRT317. B Family tree containing four carriers, JRT196, JRT216, JRT-P01, and JRT-P04. Asterisk indicates common ancestor of JRT196, JRT216, and JRTP04. C Family tree containing four carriers, JRT221, JRT342, JRT-P03, and JRT-P05. These carrier dogs are descended from a common breeding pair described in generation I. Squares and circles show males and females, respectively. The black pattern and vertical line indicate dogs with and without history of GI neoplastic polyps, respectively. The white pattern indicates dogs with unknown medical history. + , APC variant carrier; ?, APC genotype unknown 

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