From: Evaluation of safety and anti-obesity effects of DWP16001 in naturally obese dogs
Weeks | OC | DWP0.2 | DWP0.5 | DWP1 |
---|---|---|---|---|
Change rates of food consumption (%) | ||||
0 | 100.00 ± 0.00 | 100.00 ± 0.00 | 100.00 ± 0.00 | 100.00 ± 0.00 |
2 | 102.10 ± 1.31 | 126.52 ± 5.48*** | 95.13 ± 1.67*** | 100.80 ± 4.20 |
4 | 101.38 ± 1.25 | 146.64 ± 5.37*** | 92.34 ± 2.10*** | 116.02 ± 3.09*** |
6 | 99.75 ± 1.19 | 153.71 ± 4.11*** | 92.30 ± 1.60*** | 121.84 ± 2.50*** |
8 | 98.74 ± 1.41 | 168.32 ± 4.80*** | 93.64 ± 1.67* | 121.88 ± 2.36*** |
10 | 101.35 ± 2.56 | 166.59 ± 4.72*** | 98.47 ± 1.44 | 123.15 ± 2.45*** |
Change rates of resting energy requirement | ||||
0 | 100.00 ± 0.00 | 100.00 ± 0.00 | 100.00 ± 0.00 | 100.00 ± 0.00 |
2 | 99.51 ± 1.39 | 96.98 ± 2.69 | 98.63 ± 0.72 | 97.75 ± 2.32 |
4 | 99.48 ± 1.10 | 93.41 ± 5.79 | 97.93 ± 1.00 | 98.11 ± 2.18 |
6 | 98.74 ± 1.32 | 95.21 ± 4.10 | 97.54 ± 2.73 | 98.95 ± 2.07 |
8 | 99.04 ± 1.45 | 94.64 ± 3.59* | 96.92 ± 2.00 | 99.19 ± 4.05 |
10 | 99.12 ± 1.77 | 96.15 ± 4.75 | 98.79 ± 2.30 | 99.97 ± 6.15 |