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Table 2 Change rates of food consumption and resting energy requirement (%)

From: Evaluation of safety and anti-obesity effects of DWP16001 in naturally obese dogs

Weeks

OC

DWP0.2

DWP0.5

DWP1

Change rates of food consumption (%)

 0

100.00 ± 0.00

100.00 ± 0.00

100.00 ± 0.00

100.00 ± 0.00

 2

102.10 ± 1.31

126.52 ± 5.48***

95.13 ± 1.67***

100.80 ± 4.20

 4

101.38 ± 1.25

146.64 ± 5.37***

92.34 ± 2.10***

116.02 ± 3.09***

 6

99.75 ± 1.19

153.71 ± 4.11***

92.30 ± 1.60***

121.84 ± 2.50***

 8

98.74 ± 1.41

168.32 ± 4.80***

93.64 ± 1.67*

121.88 ± 2.36***

 10

101.35 ± 2.56

166.59 ± 4.72***

98.47 ± 1.44

123.15 ± 2.45***

Change rates of resting energy requirement

 0

100.00 ± 0.00

100.00 ± 0.00

100.00 ± 0.00

100.00 ± 0.00

 2

99.51 ± 1.39

96.98 ± 2.69

98.63 ± 0.72

97.75 ± 2.32

 4

99.48 ± 1.10

93.41 ± 5.79

97.93 ± 1.00

98.11 ± 2.18

 6

98.74 ± 1.32

95.21 ± 4.10

97.54 ± 2.73

98.95 ± 2.07

 8

99.04 ± 1.45

94.64 ± 3.59*

96.92 ± 2.00

99.19 ± 4.05

 10

99.12 ± 1.77

96.15 ± 4.75

98.79 ± 2.30

99.97 ± 6.15

  1. Data are expressed as Mean ± S.D
  2. OC Obese normal control, DWP0.1 DWP16001 0.2 mg/kg/day, DWP0.2 DWP16001 0.5 mg/kg/day, DWP1 DWP16001 1 mg/kg/day
  3. *A significant difference at p < 0.05 level compared to the OC
  4. **A significant difference at p<0.01 level compared to the OC
  5. ***A significant difference at p<0.001 level compared to the OC