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Table 4 Scores of ultrasonographic and radiographic evaluations (mean of the sum of the scores as shown in Tables 3 and 5) from T0 to T4 in the GC and GT

From: Effects of oral treatment with chondroitin sulfate and glucosamine in an experimental model of metacarpophalangeal osteoarthritis in horses

  

T0

T1

T2

T3

T4

P-value, Friedman test between time-points

P-value ANOVAa

Ultrasonographic

 GC

Mean ± SD

2 ± 2

6 ± 3

6 ± 3

8 ± 3

11 ± 3

0,001

 

Median (IQR)

2 (2–4)

5 (4–8)

6 (5–7)

7 (6–10)

10 (9–14)

0,564

 GT

Mean ± SD

2 ± 2

5 ± 3

6 ± 2

6 ± 1

7 ± 1

0,003

Median (IQR)

2 (0–3)

5 (3–6)

6 (4–7)

6 (6–7)

7 (6–8)

Radiographic

 GC

Mean ± SD

1 ± 1

3 ± 1

3 ± 1

2 ± 1

3 ± 2

0,005

0,361

Median (IQR)

0 (0–1)

3 (2–4)

3 (2–3)

2 (2–3)

3 (2–4)

 GT

Mean ± SD

2 ± 1

3 ± 1

2 ± 1

2 ± 1

2 ± 1

0,038

Median (IQR)

1 (1–2)

3 (2–4)

2 (1–2)

2 (1–2)

2 (2–3)

 

p-value Mann-Whitney U test between groups at each time-point

 
 

Ultrasonographic

0,645

0,645

0,798

0,336

< 0,001

  
 

Radiographic

0,051

0,79

0,123

0,872

0,597

  
  1. ANOVA analysis of variance, GC control group, SD standard deviation, GT treated group
  2. aP-value of time-points/group interaction by nonparametric two-way ANOVA