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Table 3 Predefined scores [18] for the ultrasonographic evaluation of images obtained at time-points T0 to T4

From: Effects of oral treatment with chondroitin sulfate and glucosamine in an experimental model of metacarpophalangeal osteoarthritis in horses

Ultrasound characteristics

Score

Synovial fluid appearance

 Normal (anechoic)

0

 Slightly changed (predominantly anechoic/rare hyperechogenic spots)

1

 Changed (heterogeneous liquid with anechoic points)

2

 Presence of fibrin/evident hyperechogenic spots, predominantly heterogeneous

3

Synovial fluid quantity

 Normal

0

 Slightly increased

1

 Increased

2

 Severe discharge

3

Appearance of the joint capsule (thickness and insertions)

 Normal

0

 Slightly changed (noticeable thickening and heterogeneity)

1

 Changed (clearly thickened and heterogeneous/few proliferations at insertion)

2

 Severely changed (thickened and heterogeneous, with calcification points and/or intense proliferation at insertion)

3

Appearance of periarticular ligaments (origin and insertions)

 Normal

0

 Slightly changed (noticeable heterogeneity)

1

 Changed (clearly heterogeneous and with proliferations at origin/insertion)

2

 Severely changed

3

Vascularization and synovitis

 None

0

 Mild (few vessels visible, synovium slightly hypertrophied)

1

 Moderate (evident vascularity, congestion and hypertrophied synovium)

2

 Severe

3

Appearance of articular cartilage

 Normal

0

 Slightly irregular

1

 Discontinuous and rough

2

 Difficult to visualize, erosions, fragments

3

Subchondral surface

 Normal

0

 Irregular with focal lesions

1

 Clearly irregular

2

 Depressions, erosions, fragments

3

Appearance of the plica

 Normal

0

 Mildly changed

1

 Changed (heterogeneous and hypertrophied)

2

 Severely changed

3

Presence of osteophytes

 None

0

 Mild projection

1

 Evident projection

2

 Severe projection

3

Final sum (total)

27