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Table 1 Joint angles (in degrees), visual lameness (AAEP scale) and evaluation by motion sensors (Lameness Locator) measured from T0 to T4 in the GC and GT

From: Effects of oral treatment with chondroitin sulfate and glucosamine in an experimental model of metacarpophalangeal osteoarthritis in horses

 

T0

T1

T2

T3

T4

p-value, Friedman test between time-points

p-value, ANOVAa

 

Joint angles

       

GC

Mean ± SD

138.8 ± 5.9

149 ± 3.9

150.6 ± 5.3

148.3 ± 6.5

149.5 ± 5.3

0.004

0.158

Median (IQR)

140.5 (133.5–143)

148.5 (146.5–149)

151.5 (146–154.5)

150.5 (142.5–153)

150 (146.5–153)

GT

Mean ± SD

141.8 ± 6.2

148.8 ± 5.3

147 ± 5.1

145.4 ± 2.1

148.1 ± 2.1

0.005

Median (IQR)

143.5 (140–146)

149.5 (147–151.5)

148 (143.5–150)

146 (144.5–146.5)

147.5 (146.5–149.5)

Lameness Locator

     

GC

Mean ± SD

3 ± 3

44 ± 32

33 ± 25

21 ± 13

25 ± 22

0,015

0,793

Median (IQR)

3 (0–6)

44 (22–62)

27 (14–59)

21 (14–25)

18 (11–35)

GT

Mean ± SD

1 ± 3

22 ± 20

16 ± 5

13 ± 13

11 ± 12

0,001

Median (IQR)

0 (0–2)

26 (0–35)

17 (12–21)

11 (4–19)

8 (0–19)

AAEP score

      

GC

Mean ± SD

0 ± 0

2 ± 1

2 ± 1

1 ± 1

2 ± 1

0,011

 

Median (IQR)

0 (0–0)

3 (1–3)

2 (0–3)

1 (1–2)

2 (1–2)

0,169

GT

Mean ± SD

0 ± 0

2 ± 1

2 ± 0

1 ± 1

1 ± 1

< 0,001

Median (IQR)

0 (0–0)

3 (1–3)

2 (0–3)

1 (1–2)

2 (1–2)

p-value Mann-Whitney U test between groups at each time-point

 
 

Lameness Locator

0,382

0,13

0,232

0,195

0,13

  
 

AAEP score

1

0,798

0,779

0,505

0,038

  
  1. ANOVA analysis of variance, GC control group, SD standard deviation, GT treated group
  2. aP-value of time-point/group interaction by nonparametric two-way ANOVA