Skip to main content

Table 1 Table of GWAS results for 7 candidate SNPs sorted by the highest P-value. P-value, unadjusted P-value; P-value_BH, P-value adjusted according to Benjamini-Hochberg correction; CHR, chromosome; SNP, single nucleotide polymorphism; BP, genomic position (base-pair); A1, minor allele; F_A, frequency of minor allele in long-lived group; F_U, frequency of minor allele in reference group; A2, major allele; CHISQ, basic allelic chi-square test; OR, estimated odds ratio

From: Four novel genes associated with longevity found in Cane corso purebred dogs

Gene P-value P-value_BH Position CHR SNP BP A1 F_A F_U A2 CHISQ OR
TDRP 3.705e-07 0.01006 3’UTR 25 BICF2P365740 37,486,799 T 0.7222 0.03333 C 25.84 75.4
MC2R 2.772e-05 0.09404 intron 1 BICF2P1140956 24,364,734 G 0.7778 0.1667 A 17.57 17.5
NGDN 3.969e-05 0.09404 intron 8 BICF2P384545 3,705,090 C 0.6111 0.06667 T 16.89 22
RARB 3.969e-05 0.09404 intron 23 BICF2G630382633 18,647,529 C 0.6111 0.06667 T 16.89 22
FBXO25 6.334e-05 0.138 intron 25 BICF2P999174 37,425,075 A 0.4444 0 G 16 NA
FBXL21 1.478e-04 0.1766 exon 11 chr11_23,852,542 23,852,542 T 0.6667 0.1333 C 14.4 13
PARP9 3.413e-04 0.2636 exon 33 chr33_25,671,811 25,671,811 A 0.7222 0.2 C 12.83 10.4