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Table 6 mRNA expression in tissues of 17 d old broilers fed different copper levels and sources

From: Broiler responses to copper levels and sources: growth, tissue mineral content, antioxidant status and mRNA expression of genes involved in lipid and protein metabolism

 

Breast Muscle

Liver

Intestine (jejunum)

Genes

Source

Level

S vs L

Source

Level

S x L

Source

Level

S vs L

AKT 1

0.1169

0.0450

0.1569

––

––

––

––

––

––

mTOR

0.0046

 < 0.001

0.1561

––

––

––

––

––

––

GSK 3B

0.0871

0.0057

0.0499

––

––

––

––

––

––

MT

0.8910

0.2924

0.0124

0.5524

0.0036

0.3867

0.2718

 < 0.001

 < 0.001

CuZnSOD

0.0189

 < 0.01

0.0028

 < 0.001

 < 0.001

0.2038

––

––

––

FAS

––

––

––

0.0058

0.0446

0.0097

––

––

––

LPL

––

––

––

0.1020

0.0002

0.0002

––

––

––

MDH

––

––

––

0.7833

0.0170

0.0535

––

––

––

CTR1

––

––

––

––

––

––

0.0530

0.0010

0.0144

ATOX1

––

––

––

––

––

––

0.0003

 < 0.001

0.1027

STEAP1

––

––

––

––

––

––

0.2745

0.0002

0.3132

  1. Abbreviations: AKT 1 Protein kinase serine-threonine 1, mTOR Mechanistic target of rapamycin, GSK 3B Glycogen synthase kinase, MT Metallothionein, CuZnSOD Superoxide dismutase copper-zinc, FAS Fatty Acid Synthetase, LPL Lipoprotein lipase, MDH Malate dehydrogenase, CTR1 Copper transporter 1, ATOX1 Antioxidant target 1 copper chaperone, STEAP1 Transmembrane Epithelial Antigene of the Prostate, S Source, L Level