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Table 2 Mean fasted hematology results with 95% confidence intervals for each diet group (Control, n = 5; Test, n = 6) and sampling time (baseline and 3, 14 and 28 days), as well as results of the statistical analysis (p-values). In the left column, units for each parameter are provided in parentheses and internal lab reference ranges for each parameter are provided in italics

From: Responses in randomised groups of healthy, adult Labrador retrievers fed grain-free diets with high legume inclusion for 30 days display commonalities with dogs with suspected dilated cardiomyopathy

Parameter

Sampling time

Control

Test

Statistical analysis

Mean

95% CI

Mean

95% CI

Diff. within Test diet

Diff. between diets

Red blood cell count (RBC) (1012/L)

6-9

Baseline

5.86

(5.60, 6.13)

5.82

(5.58, 6.06)

Day 3

6.09*

(5.82, 6.37)

5.74

(5.50, 5.98)

NS

0.034

Day 14

5.97

(5.71, 6.24)

5.63*

(5.40, 5.86)

0.049

0.036

Day 28

5.86

(5.60, 6.13)

5.37*

(5.15, 5.59)

< 0.001

< 0.001

Hematocrit (HCT) (%)

40-55

Baseline

45.1

(43.1, 47.1)

44.8

(43.0, 46.6)

Day 3

45.7

(43.7, 47.7)

43.4*

(41.6, 45.1)

0.035

NS

Day 14

45.3

(43.4, 47.3)

42.6*

(40.9, 44.3)

< 0.001

0.011

Day 28

45.3

(43.3, 47.3)

41.1*

(39.5, 42.8)

< 0.001

< 0.001

Total hemoglobin (HGB) (g/dL)

12-19

Baseline

15.9

(15.2, 16.7)

15.8

(15.1, 16.4)

Day 3

16.6*

(15.8, 17.3)

15.8

(15.1, 16.5)

NS

NS

Day 14

16.2

(15.5, 17.0)

15.3

(14.7, 15.9)

NS

NS

Day 28

16.4

(15.7, 17.2)

14.8*

(14.2, 15.4)

< 0.001

< 0.001

Mean cell volume (MCV) (fL)

60-77

Baseline

76.9

(75.4, 78.4)

77.0

(75.6, 78.4)

Day 3

75.1*

(73.6, 76.6)

75.6*

(74.2, 77.0)

< 0.001

NS

Day 14

75.9*

(74.4, 77.4)

75.7*

(74.3, 77.1)

< 0.001

NS

Day 28

77.3

(75.8, 78.8)

76.6

(75.2, 78.0)

NS

NS

Mean cell hemoglobin (MCH) (pg)

17-23

Baseline

27.2

(26.5, 27.9)

27.1

(26.5, 27.7)

Day 3

27.2

(26.6, 27.9)

27.5

(26.9, 28.2)

NS

NS

Day 14

27.2

(26.5, 27.8)

27.2

(26.6, 27.8)

NS

NS

Day 28

28.0*

(27.3, 28.7)

27.5

(26.9, 28.1)

NS

NS

Mean cell hemoglobin concentra-tion (MCHC) (g/dL)

31-34

Baseline

35.4

(34.7, 36.0)

35.2

(34.6, 35.8)

Day 3

36.2*

(35.6, 36.9)

36.4*

(35.9, 37.0)

< 0.001

NS

Day 14

35.8

(35.2, 36.4)

35.9*

(35.4, 36.5)

0.023

NS

Day 28

36.2*

(35.6, 36.8)

35.9*

(35.4, 36.5)

0.021

NS

Red cell distribution width (RDW) (%)

14-17

Baseline

13.3

(12.7, 13.9)

13.7

(13.1, 14.3)

Day 3

14.0*

(13.3, 14.6)

13.6

(13.0, 14.2)

NS

0.003

Day 14

14.4*

(13.8, 15.1)

13.8

(13.2, 14.3)

NS

< 0.001

Day 28

14.2*

(13.6, 14.9)

13.6

(13.0, 14.2)

NS

< 0.001

White blood cell count (WBC) (109/L)

6-12

Baseline

5.40

(4.25, 6.85)

5.41

(4.35, 6.72)

Day 3

6.28*

(4.95, 7.97)

5.35

(4.30, 6.65)

NS

0.049

Day 14

5.85

(4.61, 7.43)

5.79

(4.66, 7.20)

NS

NS

Day 28

6.01

(4.73, 7.63)

5.53

(4.45, 6.87)

NS

NS

Lymphocyte count (109/L)

1.2-3.2

Baseline

1.44

(1.17, 1.71)

1.36

(1.17, 1.71)

Day 3

1.60

(1.33, 1.87)

1.46

(1.17, 1.71)

NS

NS

Day 14

1.41

(1.14, 1.68)

1.43

(1.17, 1.71)

NS

NS

Day 28

1.66

(1.39, 1.93)

1.42

(1.17, 1.71)

NS

NS

Monocyte count (109/L)

0.3-0.8

Baseline

0.55

(0.43, 0.67)

0.53

(0.42, 0.64)

Day 3

0.61

(0.49, 0.73)

0.60*

(0.49, 0.71)

0.044

NS

Day 14

0.60

(0.48, 0.72)

0.57

(0.46, 0.68)

NS

NS

Day 28

0.64*

(0.52, 0.76)

0.58

(0.47, 0.69)

NS

NS

Eosinophil count (109/L)

1.2-6.8

Baseline

3.46

(2.51, 4.78)

3.50

(2.61, 4.70)

Day 3

3.98

(2.89, 5.50)

3.28

(2.45, 4.41)

NS

NS

Day 14

3.80

(2.75, 5.24)

3.79

(2.83, 5.09)

NS

NS

Day 28

3.62

(2.62, 5.00)

3.52

(2.63, 4.73)

NS

NS

Platelet count (PLT) (109/L)

150-500

Baseline

218

(180, 255)

186

(151, 220)

Day 3

201

(164, 239)

188

(154, 222)

NS

NS

Day 14

211

(174, 249)

173

(139, 208)

NS

NS

Day 28

199

(162, 237)

159

(124, 193)

NS

NS

Mean platelet volume (MPV) (mm3)

6.7-11.1

Baseline

7.35

(6.54, 8.16)

7.77

(7.03, 8.50)

Day 3

7.30

(6.49, 8.11)

8.07

(7.33, 8.80)

NS

NS

Day 14

7.34

(6.53, 8.15)

8.52*

(7.79, 9.26)

< 0.001

< 0.001

Day 28

7.31

(6.50, 8.12)

8.63*

(7.90, 9.37)

< 0.001

< 0.001

  1. NS no significant difference (p > 0.05)
  2. *indicate a significant change (p < 0.05) from baseline within diet group
  3. indicate significant differences (p < 0.05) in the change from baseline between diet groups, also indicated with bold values