Table 4 The pharmacokinetic parameters of UK-5099 in mice following oral or intraperitoneal administration (n = 3)
From: Determination and pharmacokinetics study of UK-5099 in mouse plasma by LC–MS/MS
Parameters (Units) | Mean ± SD |
|---|---|
Kel (h−1) | 0.052 ± 0.160 13.358 ± 0.239 |
T1/2 (h) | |
Tmax (h) | 0.250 ± 0.000 |
Cmax (ng/mL) | 82,500 ± 20,745 |
AUC0-t (h/ng/mL) | 42,103 ± 12,072 |
AUC0-inf (h/ng/mL) | 44,088 ± 12,098 |
MRT0-t (h) | 0.857 ± 0.143 |
MRT0-inf (h) | 2.227 ± 0.155 |