Fig. 2

Effects of different compounds on the growth of T. pyogenes TP13 and Pseudomonas aeruginosa PAO1 under different co-culture conditions. T. pyogenes TP13 and P. aeruginosa PAO1 were mixed and co-cultured on BHI + 5% FBS plates containing 200 μM of nitrofurantoin, ronidazole, nitrofurazone, or furazolidone from the initial ratios of (A) 1:1, (B) 1:9, and (C) 9:1, and cultured overnight at 37 °C. Data shown are the mean ± SD of three independent experiments, compare to the untreated control. One-way ANOVA, * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001