Fig. 4
From: Multimodal ocular imaging of known and novel corneal stromal disorders in dogs
A presumed pre-Descemet corneal dystrophy in case 3 has a unique appearance with corneal imaging. (A) Slit lamp biomicroscopy of case 3, an 11-month-old, male castrated French Bulldog, demonstrated subtle opacity with diffuse illumination and increase reflectivity in the posterior stroma with a narrow-slit beam. (B) and (C) Fourier-domain optical coherence tomography (FD-OCT) using 8-mm and 3-mm scan lengths demonstrated increased reflectivity anterior to Descemet’s membrane with hyperreflective particles scattered in the mid and posterior stroma. (D) In vivo confocal microscopy images (Dimensions mentioned in each image refer to the depth in the cornea at which the image has been acquired). (a) Normal superficial epithelium. (b) Normal basal epithelium. (c) Normal anterior stroma with stromal nerve and keratocytes. (d) Anterior stroma with abnormal keratocytes containing intracellular hyperreflective particles. (e) Mid-stroma with abnormal keratocytes showing extracellular and intracellular hyperreflective particles. (f) Mid-stroma with enlarged abnormal keratocytes containing intracellular hyperreflective particles. (g) Posterior stroma with abnormal keratocytes showing extracellular and intracellular hyperreflective particles. (h) Normal endothelium