Table 6 Some examples of acute phase protein (CRP: C-reactive protein; Hp: haptoglobin) response after different stimuli
Stressful condition | Reference | Animals | Sample size | Sampling times | Biomarker | Results (unless indicated, median values are expressed) | Comment |
|---|---|---|---|---|---|---|---|
Three lipopolysacharide (LPS) injections at 48 h intervals | Escribano et al. [49] | Pietrain × (Landrace × LargeWhite) growing pigs (77 days old) | 10 | 3 days before and 3 h after each LPS administration | CRP (μg/L) | From < 10 to > 60 after 1st and 2nd injections | No increased after 3rd injection |
Hp (mg/L) | From < 0.5 to > 3 after 1st injection | Still increased after 2nd and 3rd injections | |||||
Feed deprivation | Ott et al. [50] | Pietrain Plus × Rattlerow Seghers growing pigs | 24 | 24 h before, just after refeeding and 3 days after | Hp (mg/L) | Significantly increased after refeeding (~ 0.75) compared with 3 days later (< 0.5) |  |
5 days of isolation and later regrouping | Escribano et al. [51] | Duroc × (Landrace × Large White) males (190 days old) | 7 | Once a day for pre-stress period (5 days), isolation (5 days) and regrouping (3 days) | CRP and Hp | No significant differences observed with baseline or with control group (n = 7) | |