Table 6 Pharmacokinetic parameters of eugenol in tissues following a sequential immersion bath
Parameters | Unit | Hemolymph | Hepatopancreas | Muscle |
|---|---|---|---|---|
Cmax | μg/kg | 50.0 | 413.1 | 7623.0 |
Tmax | h | 1 | 4 | 1 |
t1/2z | h | 4.7 | 14.9 | 47.6 |
AUC0-t | ug/L*h | 471.8 | 1311.7 | 11,008.7 |
AUC0-∞ | ug/L*h | 481.8 | 1342.2 | 22,179.5 |
MRT0-t | h | 10.5 | 26.4 | 42.6 |
MRT0-∞ | h | 10.9 | 28.4 | 104.1 |
Vz/F | L/kg | 141.8 | 4803.2 | 928.9 |
CL/F | L/h/kg | 20.8 | 223.5 | 13.5 |