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Table 5 Plasma malondialdehyde concentration pre- and post-treatment in the control and treatment groups varying by stage in myxomatous mitral valve degenerative dogs

From: Short-term melatonin supplementation decreases oxidative stress but does not affect left ventricular structure and function in myxomatous mitral valve degenerative dogs

Control group (n = 11)

Plasma MDA (μg/mL)

Pre-treatment

Post-treatment

MMVD stage B2 (n = 5)

4.59 ± 2.87

4.70 ± 1.26

MMVD stage C (n = 6)

7.90 ± 3.30

7.06 ± 1.76

Treatment group (n = 17)

Plasma MDA (μg/mL)

Pre-treatment

Post-treatment

MMVD stage B2 (n = 6)

7.84 ± 5.71

3.48 ± 2.01

MMVD stage C (n = 11)

7.33 ± 4.22

5.05 ± 2.81 *

  1. Values are presented as mean ± SD. * P-value < 0.05 vs. Pre-treatment in the same group; MDA malondialdehyde, MMVD myxomatous mitral valve degeneration