Fig. 1

Clinical phenotype of a 2-week-old Scottish Highland calf with congenital ichthyosis, alopecia and corneal defects. Note the flat crusts lateral to the tarsi, dorsal to the metacarpi and on the bride of the nose (a). Backside of the calf with alopecia and large scales (b). Alopecia and lichenification on the neck (c). Cloudy left eye with conjunctivitis (d). The right eye shows a corneal ulceration with a prolapsed iris (e). Appearance of a typical purebred Scottish Highland cow (f)