Table 4 Serum metabolites according to SINS grades

Urea (g/dL)

SP

34.05 ± 21.26

34.65 ± 24.98

35.31 ± 18.97

− 0.032

n.s.

WP

12.67 ± 7.38

9.25 ± 5.83

6.73 ± 4.92

− 0.327

< 0.001

FA

28.71 ± 7.21

30.69 ± 7.21

39.94 ± 2.40

0.262

0.008

Creatinine (g/dL)

SP

0.56 ± 0.10

0.59 ± 0.21

0.58 ± 0.08

0.103

n.s.

WP

0.97 ± 0.20

0.96 ± 0.20

0.89 ± 0.18

− 0.085

n.s.

FA

1.86 ± 0.31

1.81 ± 0.13

1.92 ± 0.31

0.080

n.s.

Total Protein (g/dL)

SP

6.36 ± 1.37

5.83 ± 1.18

5.70 ± 0.83

− 0.200

0.032

WP

4.43 ± 0.55

4.41 ± 0.74

4.24 ± 0.76

− 0.194

0.043

FA

7.98 ± 1.24

7.27 ± 0.52

7.55 ± 0.52

−0.135

n.s.

Albumin (g/dL)

SP

1.18 ± 0.19

1.22 ± 0.40

1.16 ± 0.17

−0.065

n.s.

WP

2.69 ± 0.35

2.72 ± 0.389

2.80 ± 0.51

0.133

n.s.

FA

4.57 ± 0.64

4.26 ± 0.26

4.46 ± 0.40

−0.099

n.s.

Globulin (g/dL)

SP

5.18 ± 1.28

4.62 ± 1.04

4.54 ± 0.75

−0.220

0.019

WP

1.74 ± 0.36

1.69 ± 0.53

1.45 ± 0.41

−0.336

< 0.001

FA

3.41 ± 0.77

3.02 ± 0.61

3.10 ± 0.36

−0.209

0.034

Glucose (mg/dL)

SP

120.7 ± 25.0

117.6 ± 24.1

111.5 ± 20.0

−0.118

n.s.

WP

166.6 ± 38.6

154.0 ± 29.7

157.5 ± 36.8

−0.108

n.s.

FA

127.6 ± 45.6

133.7 ± 30.1

105.4 ± 26.3

0.093

n.s.

Bilirubin (mg/dL)

SP

0.37 ± 0.23

0.38 ± 0.21

0.29 ± 0.24

− 0.112

n.s.

WP

0.12 ± 0.08

0.09 ± 0.05

0.06 ± 0.004

− 0.349

< 0.001

FA

0.24 ± 0.15

0.22 ± 0.10

0.30 ± 0.12

0.034

n.s.

Cholesterin (mg/dL)

SP

106.3 ± 35.2

102.1 ± 30.2

105.2 ± 24.7

0.015

n.s.

WP

65.3 ± 14.3

64.2 ± 11.6

68.4 ± 11.2

0.136

n.s.

FA

103.6 ± 15.9

109.4 ± 12.4

121.0 ± 5.0

0.167

n.s.

Triglycerides (mg/dL)

SP

165.4 ± 112

129.5 ± 96.3

172.4 ± 112

0.065

n.s.

WP

41.1 ± 11.4

38.5 ± 16.6

40.3 ± 14.9

0.014

n.s.

FA

64.8 ± 21.9

70.9 ± 24.5

113.8 ± 42.9

0.307

0.002