Fig. 2

The results of non-inferiority trials relating to accuracy, sensitivity, specificity, positive and negative predictive value for COOL and ROOM at 24 and 48 h, respectively, with a non-inferiority margin set at 15% (Δ = 0.15). A-D) The lower bound of the 95% confidence interval (CI) does not fall below the noninferiority margin and non-inferiority is demonstrated for all storage methods and timepoints. E) The lower bound of the 95% CI falls below the non-inferiority margin (0.85) for the negative predictive value at 48 h and non-inferiority could thereby not be demonstrated. Remaining storage methods and timepoints demonstrates non-inferiority. COOL: Urine stored refrigerated; ROOM: Urine stored in boric acid (UriSwab™) at room temperature. Number indicates time interval since reference culture