Table 1 Demographic information, distribution of variables potentially associated with prognosis and follow-up information of 64 dogs with stage I low grade mast cell tumor treated by surgical excision and prophylactic regional lymphadenectomy or nodal observation only. Differences in data distribution were assessed with Chi-square test/Fisher’s exact test (categorical variables) or Mann-Whitney U test (quantitative variables)
Variable | Observation only (n = 35) | Prophylactic regional lymphadenectomy (n = 29) | P |
|---|---|---|---|
Purebred | Â | Â | 0.164 |
 Yes | 32 | 22 |  |
 No | 3 | 7 |  |
Breed | Â | Â | 0.078 |
 Boxer, French bulldog, Weimaraner, Pug, American Staffordishire terrier | 13 | 5 |  |
 Other | 22 | 24 |  |
Age (years) | Â | Â | 0.224 |
 Median (range) | 6.0 (2.0–11.0) | 7.0 (1.0–13.0) |  |
Weight (kg) | Â | Â | 0.237 |
 Median (range) | 33.0 (8.4–50.4) | 27.4 (5.0–55.0) |  |
Sex | Â | Â | 0.454 |
 Male | 17 | 11 |  |
 Female | 18 | 18 |  |
Neutering status | Â | Â | 0.175 |
 Yes | 27 | 17 |  |
 No | 8 | 12 |  |
Anatomic location | Â | Â | 0.137 |
 Head and neck | 8 | 8 |  |
 Trunk and limbs | 25 | 15 |  |
 Inguinal/perineal/mammary/digital | 2 | 6 |  |
Tumor diameter (cm) | Â | Â | 0.567 |
 Median (range) | 1.4 (0.5–5.4) | 1.3 (0.3–9.0) |  |
Ulceration |  |  | > 0.999 |
 Yes | 2 | 2 |  |
 No | 33 | 27 |  |
Follow-up time (days) Median (range) | 813 (290–2900) | 763 (181–2039) | 0.267 |
Disease progression | Â | Â | 0.028* |
 Yes | 6 | 0 |  |
 No | 29 | 29 |  |
Development of new MCT | Â | Â | 0.037* |
 Yes | 12 | 3 |  |
 No | 23 | 26 |  |
MCT related death | Â | Â | 0.245 |
 Yes | 3 | 0 |  |
 No | 32 | 29 |  |